MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP005576

Ontology/Pathway Information

Entrez Gene ID56950
Gene NameSET and MYND domain containing 2
Gene Symbol SMYD2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:UniProtKBCcytoplasm
GO:0005829 ISS:UniProtKBCcytosol
GO:0005634 ISS:UniProtKBCnucleus
GO:0046975 ISS:UniProtKBFhistone methyltransferase activity (H3-K36 specific)
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0002039 IPI:UniProtKBFp53 binding
GO:0016279 IDA:UniProtKBFprotein-lysine N-methyltransferase activity
GO:0000993 ISS:UniProtKBFRNA polymerase II core binding
GO:0008285 ISS:UniProtKBPnegative regulation of cell proliferation
GO:0000122 IMP:UniProtKBPnegative regulation of transcription from RNA polymerase II promoter
GO:0018027 ISS:UniProtKBPpeptidyl-lysine dimethylation
GO:0018026 IDA:UniProtKBPpeptidyl-lysine monomethylation
GO:0043516 IMP:UniProtKBPregulation of DNA damage response, signal transduction by p53 class mediator
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264165Chromatin modifying enzymes
REACT_264155Chromatin organization
REACT_268728PKMTs methylate histone lysines
  logo