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MGP005585

Record overview

MGPD IDMGP005585
Gene ID57007
SpeciesHomo sapiens (Human)
Gene Nameatypical chemokine receptor 3
Gene Symbol ACKR3
SynonymsRDC1; CXCR7; RDC-1; CMKOR1; CXC-R7; CXCR-7; GPR159;
Alternate namesatypical chemokine receptor 3; C-X-C chemokine receptor type 7; G protein-coupled receptor; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; chemokine (C-X-C motif) receptor 7; chemokine orphan receptor 1;
Chromosome2
Map Location2q37.3
SummaryThis gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ACKR3

Proteins

atypical chemokine receptor 3
Refseq ID:NP_064707
Protein GI:31083344
UniProt ID:P25106
mRNA ID:NM_020311
Length:362
RefSeq Status:
MDLHLFDYSEPGNFSDISWPCNSSDCIVVDTVMCPNMPNKSVLLYTLSFIYIFIFVIGMIANSVVVWVNIQAKTTGYDTHCYILNLAIADLWVVLTIPVW
VVSLVQHNQWPMGELTCKVTHLIFSINLFGSIFFLTCMSVDRYLSITYFTNTPSSRKKMVRRVVCILVWLLAFCVSLPDTYYLKTVTSASNNETYCRSFY
PEHSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHSSRKIIFSYVVVFLVCWLPYHVAVLLDIFSILHYIPFTCRLEHALFTALHVT
QCLSLVHCCVNPVLYSFINRNYRYELMKAFIFKYSAKTGLTKLIDASRVSETEYSALEQSTK
 
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