MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP005585

Ontology/Pathway Information

Entrez Gene ID57007
Gene Nameatypical chemokine receptor 3
Gene Symbol ACKR3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0005905 IDA:UniProtKBCcoated pit
GO:0005769 IEA:UniProtKB-SubCellCearly endosome
GO:0005768 IDA:UniProtKBCendosome
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0048471 IEA:UniProtKB-SubCellCperinuclear region of cytoplasm
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0055037 IEA:UniProtKB-SubCellCrecycling endosome
GO:0015026 IEA:InterProFcoreceptor activity
GO:0019958 IMP:UniProtKBFC-X-C chemokine binding
GO:0016494 IMP:BHF-UCLFC-X-C chemokine receptor activity
GO:0005044 IMP:UniProtKBFscavenger receptor activity
GO:0001525 IEA:InterProPangiogenesis
GO:0007155 IEA:UniProtKB-KWPcell adhesion
GO:0070098 IMP:BHF-UCLPchemokine-mediated signaling pathway
GO:0006935 IEA:InterProPchemotaxis
GO:1902230 IMP:BHF-UCLPnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0070374 IMP:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:0031623 IMP:UniProtKBPreceptor internalization
GO:0001570 IEA:InterProPvasculogenesis
GO:0016032 IEA:UniProtKB-KWPviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15344Chemokine receptors bind chemokines
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
  logo