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MGP005586

Record overview

MGPD IDMGP005586
Gene ID57016
SpeciesHomo sapiens (Human)
Gene Namealdo-keto reductase family 1, member B10 (aldose reductase)
Gene Symbol AKR1B10
SynonymsHIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12;
Alternate namesaldo-keto reductase family 1 member B10; ARP; SI reductase; aldo-keto reductase family 1, member B11 (aldose reductase-like); aldose reductase-like 1; aldose reductase-like peptide; aldose reductase-related protein; hARP; small intestine reductase;
Chromosome7
Map Location7q33
EC Number1.1.1.-
SummaryThis gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for AKR1B10

Proteins

aldo-keto reductase family 1 member B10
Refseq ID:NP_064695
Protein GI:223468663
UniProt ID:O60218
mRNA ID:NM_020299
Length:316
RefSeq Status:
MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDL
KLSYLDVYLIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYC
HSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN
VLQSSHLEDYPFNAEY
 
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