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MGP005588

Record overview

MGPD IDMGP005588
Gene ID57026
SpeciesHomo sapiens (Human)
Gene Namepyridoxal (pyridoxine, vitamin B6) phosphatase
Gene Symbol PDXP
SynonymsCIN; PLP; dJ37E16.5;
Alternate namespyridoxal phosphate phosphatase; PLP phosphatase; chronophin;
Chromosome22
Map Location22q12.3
EC Number3.1.3.3
SummaryPyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 [PubMed 14522954]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for PDXP

Proteins

pyridoxal phosphate phosphatase
Refseq ID:NP_064711
Protein GI:10092677
UniProt ID:Q96GD0
mRNA ID:NM_020315
Length:296
RefSeq Status:
MARCERLRGAALRDVLGRAQGVLFDCDGVLWNGERAVPGAPELLERLARAGKAALFVSNNSRRARPELALRFARLGFGGLRAEQLFSSALCAARLLRQRL
PGPPDAPGAVFVLGGEGLRAELRAAGLRLAGDPSAGDGAAPRVRAVLVGYDEHFSFAKLREACAHLRDPECLLVATDRDPWHPLSDGSRTPGTGSLAAAV
ETASGRQALVVGKPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRCGMTTVLTLTGVSRLEEAQAYLAAGQHDLVPHYYVESIADLTEGLED
 
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