MGP Database

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MGP005751

Ontology/Pathway Information

Entrez Gene ID64167
Gene Nameendoplasmic reticulum aminopeptidase 2
Gene Symbol ERAP2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005788 TAS:HGNCCendoplasmic reticulum lumen
GO:0005789 IEA:UniProtKB-SubCellCendoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0004177 IDA:HGNCFaminopeptidase activity
GO:0008237 IDA:HGNCFmetallopeptidase activity
GO:0008270 TAS:HGNCFzinc ion binding
GO:0019885 TAS:HGNCPantigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0008217 TAS:HGNCPregulation of blood pressure
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_75795Antigen Presentation: Folding, assembly and peptide loading of class I MHC
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_6900Immune System
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