MGP Database

MGP005786

Record overview

MGPD ID	MGP005786
Gene ID	64714
Species	Homo sapiens (Human)
Gene Name	protein disulfide isomerase family A, member 2
Gene Symbol	PDIA2
Synonyms	PDI; PDA2; PDIP; PDIR;
Alternate names	protein disulfide-isomerase A2; Rho GDP dissociation inhibitor gamma; pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; protein disulfide isomerase A2; protein disulfide isomerase, pancreatic; protein disulfide isomerase-associated 2;
Chromosome	16
Map Location	16p13.3
EC Number	5.3.4.1
Summary	Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 [PubMed 8561901]).[supplied by OMIM, Mar 2008]
Orthologs	View orthologs and multiple alignments for PDIA2

Proteins

protein disulfide-isomerase A2 precursor

Refseq ID:	NP_006840
Protein GI:	94966757
UniProt ID:	Q13087
mRNA ID:	NM_006849
Length:	525
RefSeq Status:

MSRQLLPVLLLLLLRASCPWGQEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKV
DGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALDM
TFGLTDRPRLFQQFGLTKDTVVLFKKFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAHRELLAGFGEA
APRFRGQVLFVVVDVAADNEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQ
VAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGGVLPTE
EPPEEPAAPFPEPPANSTMGSKEEL

sig_peptide: 1..21
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2380
peptide sequence: 
MSRQLLPVLLLLLLRASCPWG

mat_peptide: 22..525
product: Protein disulfide-isomerase A2
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q13087.2)
calculated_mol_wt: 55845
peptide sequence: 
QEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLK
FFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALDMTFGLTDRPRLFQQFGLTKDTV
VLFKKFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVAADNEH
VLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHC
KEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGGVLPTEEPPEEPAAPFPEPPANSTMGS
KEEL