MGP Database

MGP005787

Record overview

MGPD ID	MGP005787
Gene ID	64754
Species	Homo sapiens (Human)
Gene Name	SET and MYND domain containing 3
Gene Symbol	SMYD3
Synonyms	KMT3E; ZMYND1; ZNFN3A1; bA74P14.1;
Alternate names	histone-lysine N-methyltransferase SMYD3; SET and MYND domain-containing protein 3; bA74P14.1 (novel protein); zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing), 1; zinc finger, MYND domain containing 1;
Chromosome	1
Map Location	1q44
EC Number	2.1.1.43
Summary	This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Orthologs	View orthologs and multiple alignments for SMYD3

Proteins

histone-lysine N-methyltransferase SMYD3 isoform 1

Refseq ID:	NP_001161212
Protein GI:	267844824
UniProt ID:	Q9H7B4
mRNA ID:	NM_001167740
Length:	428
RefSeq Status:

MEPLKVEKFATAKRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEKLMRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPD
SVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPS
ISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCFECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHW
KWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYRIFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIM
RVTHGREHSLIEDLILLLEECDANIRAS

histone-lysine N-methyltransferase SMYD3 isoform 2

Refseq ID:	NP_073580
Protein GI:	12232401
UniProt ID:	Q9H7B4
mRNA ID:	NM_022743
Length:	369
RefSeq Status:

`MRCSQCRVAKYCSAKCQKKAWPDHKRECKCLKSCKPRYPPDSVRLLGRVVFKLMDGAPSESEKLYSFYDLESNINKLTEDKKEGLRQLVMTFQHFMREEI QDASQLPPAFDLFEAFAKVICNSFTICNAEMQEVGVGLYPSISLLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEELTICYLDMLMTSEERRKQLRDQYCF ECDCFRCQTQDKDADMLTGDEQVWKEVQESLKKIEELKAHWKWEQVLAMCQAIISSNSERLPDINIYQLKVLDCAMDACINLGLLEEALFYGTRTMEPYR IFFPGSHPVRGVQVMKVGKLQLHQGMFPQAMKNLRLAFDIMRVTHGREHSLIEDLILLLEECDANIRAS`