MGP Database

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MGP005803

Record overview

MGPD IDMGP005803
Gene ID64902
SpeciesHomo sapiens (Human)
Gene Namealanine--glyoxylate aminotransferase 2
Gene Symbol AGXT2
SynonymsAGT2; DAIBAT;
Alternate namesalanine--glyoxylate aminotransferase 2, mitochondrial; (R)-3-amino-2-methylpropionate--pyruvate transaminase; beta-ALAAT II; beta-alanine-pyruvate aminotransferase;
Chromosome5
Map Location5p13
EC Number2.6.1.44
SummaryThe protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. [provided by RefSeq, Dec 2008]
OrthologsView orthologs and multiple alignments for AGXT2

Proteins

alanine--glyoxylate aminotransferase 2, mitochondrial precursor
Refseq ID:NP_114106
Protein GI:13994255
UniProt ID:Q9BYV1
mRNA ID:NM_031900
Length:514
RefSeq Status:
MTLIWRHLLRPLCLVTSAPRILEMHPFLSLGTSRTSVTKLSLHTKPRMPPCDFMPERYQSLGYNRVLEIHKEHLSPVVTAYFQKPLLLHQGHMEWLFDAE
GSRYLDFFSGIVTVSVGHCHPKVNAVAQKQLGRLWHTSTVFFHPPMHEYAEKLAALLPEPLKVIFLVNSGSEANELAMLMARAHSNNIDIISFRGAYHGC
SPYTLGLTNVGTYKMELPGGTGCQPTMCPDVFRGPWGGSHCRDSPVQTIRKCSCAPDCCQAKDQYIEQFKDTLSTSVAKSIAGFFAEPIQGVNGVVQYPK
GFLKEAFELVRARGGVCIADEVQTGFGRLGSHFWGFQTHDVLPDIVTMAKGIGNGFPMAAVITTPEIAKSLAKCLQHFNTFGGNPMACAIGSAVLEVIKE
ENLQENSQEVGTYMLLKFAKLRDEFEIVGDVRGKGLMIGIEMVQDKISCRPLPREEVNQIHEDCKHMGLLVGRGSIFSQTFRIAPSMCITKPEVDFAVEV
FRSALTQHMERRAK
 
transit_peptide: 1..41
calculated_mol_wt: 4677
peptide sequence: 
MTLIWRHLLRPLCLVTSAPRILEMHPFLSLGTSRTSVTKLS

mat_peptide: 42..514
product: alanine--glyoxylate aminotransferase 2, mitochondrial
calculated_mol_wt: 52498
peptide sequence: 
LHTKPRMPPCDFMPERYQSLGYNRVLEIHKEHLSPVVTAYFQKPLLLHQGHMEWLFDAEGSRYLDFFSGIVTVSVGHCHPKVNAVAQKQLGRLWHTSTVF
FHPPMHEYAEKLAALLPEPLKVIFLVNSGSEANELAMLMARAHSNNIDIISFRGAYHGCSPYTLGLTNVGTYKMELPGGTGCQPTMCPDVFRGPWGGSHC
RDSPVQTIRKCSCAPDCCQAKDQYIEQFKDTLSTSVAKSIAGFFAEPIQGVNGVVQYPKGFLKEAFELVRARGGVCIADEVQTGFGRLGSHFWGFQTHDV
LPDIVTMAKGIGNGFPMAAVITTPEIAKSLAKCLQHFNTFGGNPMACAIGSAVLEVIKEENLQENSQEVGTYMLLKFAKLRDEFEIVGDVRGKGLMIGIE
MVQDKISCRPLPREEVNQIHEDCKHMGLLVGRGSIFSQTFRIAPSMCITKPEVDFAVEVFRSALTQHMERRAK
 
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