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MGP005859

Record overview

MGPD IDMGP005859
Gene ID79143
SpeciesHomo sapiens (Human)
Gene Namemembrane bound O-acyltransferase domain containing 7
Gene Symbol MBOAT7
SynonymsBB1; LRC4; LENG4; LPIAT; MBOA7; OACT7; hMBOA-7;
Alternate nameslysophospholipid acyltransferase 7; 1-acylglycerophosphatidylinositol O-acyltransferase; LPLAT 7; bladder and breast carcinoma-overexpressed gene 1 protein; h-mboa-7; leukocyte receptor cluster (LRC) member 4; lyso-PI acyltransferase; lysophosphatidylinositol acyltransferase; malignant cell expression-enhanced gene/tumor progression-enhanced;
Chromosome19
Map Location19q13.4
EC Number2.3.1.-
SummaryThis gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity. The encoded protein is a lysophosphatidylinositol acyltransferase that has specificity for arachidonoyl-CoA as an acyl donor. This protein is involved in the reacylation of phospholipids as part of the phospholipid remodeling pathway known as the Land cycle. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
OrthologsView orthologs and multiple alignments for MBOAT7

Proteins

lysophospholipid acyltransferase 7 isoform 1
Refseq ID:NP_077274
Protein GI:225703079
UniProt ID:Q96N66
mRNA ID:NM_024298
Length:472
RefSeq Status:
MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPF
TNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL
FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIR
NIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHW
FLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE
 
lysophospholipid acyltransferase 7 isoform 2
Refseq ID:NP_001139555
Protein GI:225703033
UniProt ID:Q96N66
mRNA ID:NM_001146083
Length:399
RefSeq Status:
MGSSRCGPGAHPVHLWPPHFAFSGHHPRDLGPHSGPALLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTY
LDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAG
GGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCL
AAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE
 
lysophospholipid acyltransferase 7 isoform 2
Refseq ID:NP_001139528
Protein GI:225703081
UniProt ID:Q96N66
mRNA ID:NM_001146056
Length:399
RefSeq Status:
Protein sequence is identical to GI:225703033 (mRNA isoform)
 
lysophospholipid acyltransferase 7 isoform 3
Refseq ID:NP_001139554
Protein GI:225703037
UniProt ID:Q96N66
mRNA ID:NM_001146082
Length:344
RefSeq Status:
MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPF
TNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL
FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIR
NIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLR
 
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