MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP005891

Record overview

MGPD IDMGP005891
Gene ID79646
SpeciesHomo sapiens (Human)
Gene Namepantothenate kinase 3
Gene Symbol PANK3
Alternate namespantothenate kinase 3; hPanK3; pantothenic acid kinase 3;
Chromosome5
Map Location5q34
EC Number2.7.1.33
SummaryThis gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PANK3

Proteins

pantothenate kinase 3
Refseq ID:NP_078870
Protein GI:13375789
UniProt ID:Q9H999
mRNA ID:NM_024594
Length:370
RefSeq Status:
MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGR
DKNFSTLQTVLCATGGGAYKFEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLDDPYPLLVVNIGSGVSILAVH
SKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNN
IGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPNFS
 
  logo