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MGP Database

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MGP005896

Ontology/Pathway Information

Entrez Gene ID	79671
Gene Name	NLR family member X1
Gene Symbol	NLRX1
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005741	TAS:Reactome	C	mitochondrial outer membrane
GO:0005524	IEA:UniProtKB-KW	F	ATP binding
GO:0045087	TAS:Reactome	P	innate immune response
GO:0043124	IEA:Ensembl	P	negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050728	IEA:Ensembl	P	negative regulation of inflammatory response
GO:0045824	IEA:Ensembl	P	negative regulation of innate immune response
GO:0032688	IEA:Ensembl	P	negative regulation of interferon-beta production
GO:0032715	IEA:Ensembl	P	negative regulation of interleukin-6 production
GO:0039536	IEA:Ensembl	P	negative regulation of RIG-I signaling pathway
GO:0032480	TAS:Reactome	P	negative regulation of type I interferon production
GO:0016032	IEA:UniProtKB-KW	P	viral process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_6900	Immune System
REACT_6802	Innate Immune System
REACT_25271	Negative regulators of RIG-I/MDA5 signaling
REACT_25359	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways