MGP Database

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MGP005947

Ontology/Pathway Information

Entrez Gene ID79971
Gene Namewntless Wnt ligand secretion mediator
Gene Symbol WLS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030659 IEA:UniProtKB-SubCellCcytoplasmic vesicle membrane
GO:0032839 IEA:EnsemblCdendrite cytoplasm
GO:0032590 IEA:EnsemblCdendrite membrane
GO:0031901 TAS:ReactomeCearly endosome membrane
GO:0000139 TAS:ReactomeCGolgi membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0004871 ISS:UniProtKBFsignal transducer activity
GO:0009948 IEA:EnsemblPanterior/posterior axis specification
GO:0001707 IEA:EnsemblPmesoderm formation
GO:0090263 IMP:BHF-UCLPpositive regulation of canonical Wnt signaling pathway
GO:0043123 ISS:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016055 IEA:UniProtKB-KWPWnt signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_116125Disease
REACT_11045Signaling by Wnt
REACT_264125Signaling by WNT in cancer
REACT_111102Signal Transduction
REACT_163710WNT ligand biogenesis and trafficking
REACT_263933WNT ligand secretion is abrogated by the PORCN inhibitor LGK974
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