MGP Database

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MGP005965

Record overview

MGPD IDMGP005965
Gene ID80143
SpeciesHomo sapiens (Human)
Gene Namesuppressor of IKBKE 1
Gene Symbol SIKE1
SynonymsSIKE;
Alternate namessuppressor of IKBKE 1; suppressor of IKK epsilon; suppressor of IKK-epsilon;
Chromosome1
Map Location1p13.2
SummarySIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for SIKE1

Proteins

suppressor of IKBKE 1 isoform 1
Refseq ID:NP_001095866
Protein GI:156151379
UniProt ID:Q9BRV8
mRNA ID:NM_001102396
Length:211
RefSeq Status:
MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEE
HQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKE
NSMDTASQAIK
 
suppressor of IKBKE 1 isoform 2
Refseq ID:NP_079349
Protein GI:156151377
UniProt ID:Q9BRV8
mRNA ID:NM_025073
Length:207
RefSeq Status:
MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDA
LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKENSMD
TASQAIK
 
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