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MGP006078

Record overview

MGPD IDMGP006078
Gene ID83594
SpeciesHomo sapiens (Human)
Gene Namenudix (nucleoside diphosphate linked moiety X)-type motif 12
Gene Symbol NUDT12
Alternate namesperoxisomal NADH pyrophosphatase NUDT12; nucleoside diphosphate linked moiety X-type motif 12; nucleoside diphosphate-linked moiety X motif 12; nudix motif 12;
Chromosome5
Map Location5q21.2
EC Number3.6.1.22
SummaryNucleotides are involved in numerous biochemical reactions and pathways within the cell as substrates, cofactors, and effectors. Nudix hydrolases, such as NUDT12, regulate the concentrations of individual nucleotides and of nucleotide ratios in response to changing circumstances (Abdelraheim et al., 2003 [PubMed 12790796]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for NUDT12

Proteins

peroxisomal NADH pyrophosphatase NUDT12 isoform 1
Refseq ID:NP_113626
Protein GI:13899267
UniProt ID:Q9BQG2
mRNA ID:NM_031438
Length:462
RefSeq Status:
MSSVKRSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLAT
AKGGKKPWFLTNEVEECENYFSKTLLDRKSEKRNNSDWLLAKESHPATVFILFSDLNPLVTLGGNKESFQQPEVRLCQLNYTDIKDYLAQPEKITLIFLG
VELEIKDKLLNYAGEVPREEEDGLVAWFALGIDPIAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNATKIEEGGYKR
LCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVACQPWPMPSSLMIGC
LALAVSTEIKVDKNEIEDARWFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
 
peroxisomal NADH pyrophosphatase NUDT12 isoform 2
Refseq ID:NP_001287670
Protein GI:663429597
UniProt ID:Q9BQG2
mRNA ID:NM_001300741
Length:444
RefSeq Status:
MSSVKRSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECE
NYFSKTLLDRKSEKRNNSDWLLAKESHPATVFILFSDLNPLVTLGGNKESFQQPEVRLCQLNYTDIKDYLAQPEKITLIFLGVELEIKDKLLNYAGEVPR
EEEDGLVAWFALGIDPIAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNATKIEEGGYKRLCLKEDCPSLNGVHNTSY
PRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVACQPWPMPSSLMIGCLALAVSTEIKVDKNEIED
ARWFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
 
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