MGP Database

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MGP006159

Ontology/Pathway Information

Entrez Gene ID84678
Gene Namelysine (K)-specific demethylase 2B
Gene Symbol KDM2B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005730 IEA:UniProtKB-SubCellCnucleolus
GO:0005634 NAS:UniProtKBCnucleus
GO:0003677 NAS:UniProtKBFDNA binding
GO:0032452 TAS:BHF-UCLFhistone demethylase activity
GO:0051864 IEA:UniProtKB-ECFhistone demethylase activity (H3-K36 specific)
GO:0019843 IEA:UniProtKB-KWFrRNA binding
GO:0008270 IEA:InterProFzinc ion binding
GO:0048596 ISS:BHF-UCLPembryonic camera-type eye morphogenesis
GO:0030900 ISS:BHF-UCLPforebrain development
GO:0021592 ISS:BHF-UCLPfourth ventricle development
GO:0030902 ISS:BHF-UCLPhindbrain development
GO:0016577 TAS:GOCPhistone demethylation
GO:0035518 IDA:UniProtKBPhistone H2A monoubiquitination
GO:0021993 ISS:BHF-UCLPinitiation of neural tube closure
GO:0021670 ISS:BHF-UCLPlateral ventricle development
GO:0030901 ISS:BHF-UCLPmidbrain development
GO:0021555 ISS:BHF-UCLPmidbrain-hindbrain boundary morphogenesis
GO:2000178 ISS:BHF-UCLPnegative regulation of neural precursor cell proliferation
GO:0043524 ISS:BHF-UCLPnegative regulation of neuron apoptotic process
GO:0000122 ISS:BHF-UCLPnegative regulation of transcription from RNA polymerase II promoter
GO:0007283 ISS:BHF-UCLPspermatogenesis
GO:0021678 ISS:BHF-UCLPthird ventricle development
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264165Chromatin modifying enzymes
REACT_264155Chromatin organization
REACT_263961HDMs demethylate histones
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