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MGP006164

Record overview

MGPD IDMGP006164
Gene ID84706
SpeciesHomo sapiens (Human)
Gene Nameglutamic pyruvate transaminase (alanine aminotransferase) 2
Gene Symbol GPT2
SynonymsALT2;
Alternate namesalanine aminotransferase 2; GPT 2; glutamate pyruvate transaminase 2; glutamic--alanine transaminase 2; glutamic--pyruvic transaminase 2; glutamic-pyruvate transaminase 2;
Chromosome16
Map Location16q12.1
EC Number2.6.1.2
SummaryThis gene encodes one of the two pyridoxal enzymes which catalyze a reversible transamination reaction to yield glutamate and pyruvate so these enzymes participate in amino acid metabolism and gluconeogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
OrthologsView orthologs and multiple alignments for GPT2

Proteins

alanine aminotransferase 2 isoform 1
Refseq ID:NP_597700
Protein GI:19263340
UniProt ID:Q8TD30
mRNA ID:NM_133443
Length:523
RefSeq Status:
MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERILTLESMNPQVKAVEYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQA
MGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVS
GGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADE
VYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFE
QFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPP
VEKLKTVLQKVKDFHINFLEKYA
 
alanine aminotransferase 2 isoform 2
Refseq ID:NP_001135938
Protein GI:215599424
UniProt ID:Q8TD30
mRNA ID:NM_001142466
Length:423
RefSeq Status:
MGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVS
GGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADE
VYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFE
QFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPP
VEKLKTVLQKVKDFHINFLEKYA
 
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