MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP006168

Record overview

MGPD IDMGP006168
Gene ID84735
SpeciesHomo sapiens (Human)
Gene Namecarnosine dipeptidase 1 (metallopeptidase M20 family)
Gene Symbol CNDP1
SynonymsCN1; CPGL2; HsT2308;
Alternate namesbeta-Ala-His dipeptidase; CNDP dipeptidase 1; carnosinase 1; glutamate carboxypeptidase-like protein 2; serum carnosinase;
Chromosome18
Map Location18q22.3
EC Number3.4.13.20
SummaryThis gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CNDP1

Proteins

beta-Ala-His dipeptidase precursor
Refseq ID:NP_116038
Protein GI:21071039
UniProt ID:Q96KN2
mRNA ID:NM_032649
Length:507
RefSeq Status:
MDPKLGRMAASLLAVLLLLLERGMFSSPSPPPALLEKVFQYIDLHQDEFVQTLKEWVAIESDSVQPVPRFRQELFRMMAVAADTLQRLGARVASVDMGPQ
QLPDGQSLPIPPVILAELGSDPTKGTVCFYGHLDVQPADRGDGWLTDPYVLTEVDGKLYGRGATDNKGPVLAWINAVSAFRALEQDLPVNIKFIIEGMEE
AGSVALEELVEKEKDRFFSGVDYIVISDNLWISQRKPAITYGTRGNSYFMVEVKCRDQDFHSGTFGGILHEPMADLVALLGSLVDSSGHILVPGIYDEVV
PLTEEEINTYKAIHLDLEEYRNSSRVEKFLFDTKEEILMHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVIGKFSIRLVPHMNVSAVEKQVTRHLEDVFSK
RNSSNKMVVSMTLGLHPWIANIDDTQYLAAKRAIRTVFGTEPDMIRDGSTIPIAKMFQEIVHKSVVLIPLGAVDDGEHSQNEKINRWNYIEGTKLFAAFF
LEMAQLH
 
sig_peptide: 1..26
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2847
peptide sequence: 
MDPKLGRMAASLLAVLLLLLERGMFS
 
  logo