MGP Database

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MGP006450

Record overview

MGPD IDMGP006450
Gene ID124975
SpeciesHomo sapiens (Human)
Gene Namegamma-glutamyltransferase 6
Gene Symbol GGT6
Alternate namesgamma-glutamyltransferase 6; gamma-glutamyltransferase 6 homolog; gamma-glutamyltranspeptidase 6; glutathione hydrolase 6;
Chromosome17
Map Location17p13.2
EC Number2.3.2.2
SummaryGGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]
OrthologsView orthologs and multiple alignments for GGT6

Proteins

gamma-glutamyltransferase 6 isoform a
Refseq ID:NP_001116362
Protein GI:171543825
UniProt ID:Q6P531
mRNA ID:NM_001122890
Length:493
RefSeq Status:
MERAEEPVVYQKLLPWEPSLESEEEVEEEETSEALVLNPRRHQDSSRNKAGGLPGTWARVVAALLLLAVGCSLAVRQLQNQGRSTGSLGSVAPPPGGHSH
GPGVYHHGAIISPAGRELLVAGGNVVDAGVGAALCLAVVHPHATGLGAMFWGLFHDSSSGNSTALTSGPAQTLAPGLGLPAALPTLHLLHARFGRLPWPR
LLVGPTTLAQEGFLVDTPLARALVARGTEGLCPLLCHADGTPLGAGARATNPQLAAVLRSAALAPTSDLAGDALLSLLAGDLGVEVPSAVPRPTLEPAEQ
LPVPQGILFTTPSPSAGPELLALLEAALRSGAPIPDPCPPFLQTAVSPESSALAAVDSSGSVLLLTSSLNCSFGSAHLSPSTGVLLSNLVAKSTTSAWAC
PLILRGSLDDTEADVLGLVASGTPDVARAMTHTLLRHLAARPPTQAQHQHQGQQEPTEHPSTCGQGTLLQVAAHTEHAHVSSVPHACCPFQGF
 
gamma-glutamyltransferase 6 isoform b
Refseq ID:NP_699169
Protein GI:171543823
UniProt ID:Q6P531
mRNA ID:NM_153338
Length:461
RefSeq Status:
MERAEEPVVYQKLLPWEPSLESEEEVEEEETSEALVLNPRRHQDSSRNKAGGLPGTWARVVAALLLLAVGCSLAVRQLQNQGRSTGSLGSVAPPPGGHSH
GPGVYHHGAIISPAGAMFWGLFHDSSSGNSTALTSGPAQTLAPGLGLPAALPTLHLLHARFGRLPWPRLLVGPTTLAQEGFLVDTPLARALVARGTEGLC
PLLCHADGTPLGAGARATNPQLAAVLRSAALAPTSDLAGDALLSLLAGDLGVEVPSAVPRPTLEPAEQLPVPQGILFTTPSPSAGPELLALLEAALRSGA
PIPDPCPPFLQTAVSPESSALAAVDSSGSVLLLTSSLNCSFGSAHLSPSTGVLLSNLVAKSTTSAWACPLILRGSLDDTEADVLGLVASGTPDVARAMTH
TLLRHLAARPPTQAQHQHQGQQEPTEHPSTCGQGTLLQVAAHTEHAHVSSVPHACCPFQGF
 
gamma-glutamyltransferase 6 isoform c
Refseq ID:NP_001275631
Protein GI:569026873
UniProt ID:Q6P531
mRNA ID:NM_001288702
Length:499
RefSeq Status:
MERAEEPVVYQKLLPWEPSLESEEEVEEEETSEALVLNPRRHQDSSRNKAGGLPGTWARVVAALLLLAVGCSLAVRQLQNQGRSTGSLGSVAPPPGGHSH
GPGVYHHGAIISPAATCSHLGRELLVAGGNVVDAGVGAALCLAVVHPHATGLGAMFWGLFHDSSSGNSTALTSGPAQTLAPGLGLPAALPTLHLLHARFG
RLPWPRLLVGPTTLAQEGFLVDTPLARALVARGTEGLCPLLCHADGTPLGAGARATNPQLAAVLRSAALAPTSDLAGDALLSLLAGDLGVEVPSAVPRPT
LEPAEQLPVPQGILFTTPSPSAGPELLALLEAALRSGAPIPDPCPPFLQTAVSPESSALAAVDSSGSVLLLTSSLNCSFGSAHLSPSTGVLLSNLVAKST
TSAWACPLILRGSLDDTEADVLGLVASGTPDVARAMTHTLLRHLAARPPTQAQHQHQGQQEPTEHPSTCGQGTLLQVAAHTEHAHVSSVPHACCPFQGF
 
gamma-glutamyltransferase 6 isoform d
Refseq ID:NP_001275632
Protein GI:569026718
UniProt ID:Q6P531
mRNA ID:NM_001288703
Length:198
RefSeq Status:
MERAEEPVVYQKLLPWEPSLESEEEVEEEETSEALVLNPRRHQDSSRNKAGGLPGTWARVVAALLLLAVGCSLAVRQLQNQGRSTGSLGSVAPPPGGHSH
GPGVYHHGAIISPAGRELLVAGGNVVDAGVGAALCLAVVHPHATGLDCCEPREQCPGRRGQQRLCAPSHLLAQLLLWLCTPVPKHWGSAQQPGGQVYH
 
gamma-glutamyltransferase 6 isoform e
Refseq ID:NP_001275633
Protein GI:569026715
UniProt ID:Q6P531
mRNA ID:NM_001288704
Length:166
RefSeq Status:
MERAEEPVVYQKLLPWEPSLESEEEVEEEETSEALVLNPRRHQDSSRNKAGGLPGTWARVVAALLLLAVGCSLAVRQLQNQGRSTGSLGSVAPPPGGHSH
GPGVYHHGAIISPADCCEPREQCPGRRGQQRLCAPSHLLAQLLLWLCTPVPKHWGSAQQPGGQVYH
 
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