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MGP006450

UniProt Annotations

Entry Information
Gene Namegamma-glutamyltransferase 6
Protein EntryGGT6_HUMAN
UniProt IDQ6P531
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6P531-1; Sequence=Displayed; Name=2; IsoId=Q6P531-2; Sequence=VSP_030451;
Catalytic ActivityA (5-L-glutamyl)-peptide + an amino acid = a peptide + a 5-L-glutamyl amino acid.
Catalytic ActivityGlutathione + H(2)O = L-cysteinylglycine + L- glutamate.
FunctionCleaves glutathione conjugates. {ECO:0000250}.
PathwaySulfur metabolism; glutathione metabolism.
SimilarityBelongs to the gamma-glutamyltransferase family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
SubunitHeterodimer composed of the light and heavy chains. The active site is located in the light chain (By similarity). {ECO:0000250}.
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