MGP Database

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MGP006612

Ontology/Pathway Information

Entrez Gene ID146850
Gene Namephosphoinositide-3-kinase, regulatory subunit 6
Gene Symbol PIK3R6
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0016020 ISS:UniProtKBCmembrane
GO:0005944 ISS:UniProtKBCphosphatidylinositol 3-kinase complex, class IB
GO:0046935 ISS:UniProtKBF1-phosphatidylinositol-3-kinase regulator activity
GO:0046934 IEA:EnsemblFphosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0001525 IEA:UniProtKB-KWPangiogenesis
GO:0007596 TAS:ReactomePblood coagulation
GO:0007186 ISS:UniProtKBPG-protein coupled receptor signaling pathway
GO:0006661 TAS:ReactomePphosphatidylinositol biosynthetic process
GO:0006644 TAS:ReactomePphospholipid metabolic process
GO:0030168 TAS:ReactomePplatelet activation
GO:0045766 IMP:UniProtKBPpositive regulation of angiogenesis
GO:0043406 ISS:UniProtKBPpositive regulation of MAP kinase activity
GO:0043551 ISS:GOCPregulation of phosphatidylinositol 3-kinase activity
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_19290G beta:gamma signalling through PI3Kgamma
REACT_19184GPCR downstream signaling
REACT_19388G-protein beta:gamma signalling
REACT_1695GPVI-mediated activation cascade
REACT_604Hemostasis
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_120870Phospholipid metabolism
REACT_121175PI Metabolism
REACT_798Platelet activation, signaling and aggregation
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_121025Synthesis of PIPs at the plasma membrane
SMP Pathway Links
SMP IDDescription
SMP00391Insulin Signalling
SMP00682Leucine Stimulation on Insulin Signaling
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