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MGP006829

Record overview

MGPD IDMGP006829
Gene ID221823
SpeciesHomo sapiens (Human)
Gene Namephosphoribosyl pyrophosphate synthetase 1-like 1
Gene Symbol PRPS1L1
SynonymsPRPS1; PRPS3; PRPSL; PRS-III;
Alternate namesribose-phosphate pyrophosphokinase 3; PRPS1-like 1; phosphoribosyl pyrophosphate synthase 1-like 1; phosphoribosyl pyrophosphate synthase III; phosphoribosylpyrophosphate synthetase subunit III; ribose-phosphate diphosphokinase catalytic chain III; ribose-phosphate pyrophosphokinase III;
Chromosome7
Map Location7p21.1
EC Number2.7.6.1
SummaryThis intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for PRPS1L1

Proteins

ribose-phosphate pyrophosphokinase 3
Refseq ID:NP_787082
Protein GI:28557709
UniProt ID:P21108
mRNA ID:NM_175886
Length:318
RefSeq Status:
MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGCGEINDSLMELLIMINACKIASASRVTAVIPCFPYARQDKK
DKSRSPISAKLVANMLSIAGADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTSIADQLNVDFALIHKERKKAN
EVDCIVLVGDVNDRVAILVDDMADTCVTICLAADKLLSAGATRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISMILAEAI
RRTHNGESVSYLFSHVPL
 
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