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MGP006870

Record overview

MGPD IDMGP006870
Gene ID254531
SpeciesHomo sapiens (Human)
Gene Namelysophosphatidylcholine acyltransferase 4
Gene Symbol LPCAT4
SynonymsAYTL3; AGPAT7; LPEAT2; LPAAT-eta;
Alternate nameslysophospholipid acyltransferase LPCAT4; 1-AGP acyltransferase 7; 1-AGPAT 7; 1-acylglycerol-3-phosphate O-acyltransferase 7 (lysophosphatidic acid acyltransferase, eta); 1-acylglycerophosphocholine O-acyltransferase; 1-acylglycerophosphoserine O-acyltransferase; 1-alkenylglycerophosphoethanolamine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; PLSC domain containing protein; acyl-CoA:lysophosphatidylethanolamine acyltransferase 2; acyltransferase like 3; acyltransferase-like 3; lysophosphatidylethanolamine acyltransferase 2; plasmalogen synthase;
Chromosome15
Map Location15q14
EC Number2.3.1.23
SummaryMembers of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]).[supplied by OMIM, May 2008]
OrthologsView orthologs and multiple alignments for LPCAT4

Proteins

lysophospholipid acyltransferase LPCAT4
Refseq ID:NP_705841
Protein GI:87116681
UniProt ID:Q643R3
mRNA ID:NM_153613
Length:524
RefSeq Status:
MSQGSPGDWAPLDPTPGPPASPNPFVHELHLSRLQRVKFCLLGALLAPIRVLLAFIVLFLLWPFAWLQVAGLSEEQLQEPITGWRKTVCHNGVLGLSRLL
FFLLGFLRIRVRGQRASRLQAPVLVAAPHSTFFDPIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGKWPQVLF
FPEGTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYHPSPEESRDPTLYANNVQRVMAQALGIP
ATECEFVGSLPVIVVGRLKVALEPQLWELGKVLRKAGLSAGYVDAGAEPGRSRMISQEEFARQLQLSDPQTVAGAFGYFQQDTKGLVDFRDVALALAALD
GGRSLEELTRLAFELFAEEQAEGPNRLLYKDGFSTILHLLLGSPHPAATALHAELCQAGSSQGLSLCQFQNFSLHDPLYGKLFSTYLRPPHTSRGTSQTP
NASSPGNPTALANGTVQAPKQKGD
 
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