Summary of Study ST001839
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001161. The data can be accessed directly via it's Project DOI: 10.21228/M8N11H This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001839 |
Study Title | Metabolite profiling of Malaysian Gracilaria edulis reveals Eplerenone as novel antibacterial compound for drug repurposing against MDR Bacteria |
Study Type | In vitro antibacterial studies |
Study Summary | The current study re-defines a method to reveal bioactive compounds from the crude extracts of Malaysian red seaweed Gracilaria edulis, having promising antibacterial activities against selected bacterial species. Three species of Gram-positive and - negative characters were remarkably inhibited by the sequential and direct extracts of ethyl acetate and acetone. These were further separated through chromatographic methods to reveal a plethora of chemical constituents to be considered for a downstream virtual screening against selected crucial proteins of the six bacteria. |
Institute | Sunway University |
Department | Biological Sciences, Sunway University, Selangor, Malaysia |
Laboratory | Disease Complexity |
Last Name | Lahiri |
First Name | Chandrajit |
Address | Sunway University, No. 5, Jalan Universiti, Bandar Sunway, Petaling Jaya 47500, Selangor, Malaysia |
chandrajitl@sunway.edu.my | |
Phone | +60 3 7491 8622 |
Submit Date | 2021-04-13 |
Raw Data Available | Yes |
Analysis Type Detail | LC-MS |
Release Date | 2021-10-20 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Other organism; Subject species: Gracilaria edulis (Factor headings shown in green)
mb_sample_id | local_sample_id | Solvent |
---|---|---|
SA171097 | GE-GC-AC(d) | Acetone | Treatment:Direct |
SA171098 | GE-GC-AC(s) | Acetone | Treatment:Sequential |
SA171099 | GE-LC-AC(s) | Acetone | Treatment:Sequential |
SA171100 | BL-GC-AC(d) | Blank(Acetone) | Treatment:Direct |
SA171101 | BL-GC-AC(s) | Blank(Acetone) | Treatment:Sequential |
SA171102 | BL-GC-EA(d) | Blank(Ethyl acetate) | Treatment:Direct |
SA171103 | BL-GC-EA(s) | Blank(Ethyl acetate) | Treatment:Sequential |
SA171104 | BL-LC-MT(s) | Blank(Methanol) | Treatment:Sequential |
SA171105 | GE-GC-EA(d) | Ethyl acetate | Treatment:Direct |
SA171106 | GE-GC-EA(s) | Ethyl acetate | Treatment:Sequential |
SA171107 | GE-LC-EA(s) | Ethyl acetate | Treatment:Sequential |
Showing results 1 to 11 of 11 |