Summary of Study ST001839
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001161. The data can be accessed directly via it's Project DOI: 10.21228/M8N11H This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001839 |
| Study Title | Metabolite profiling of Malaysian Gracilaria edulis reveals Eplerenone as novel antibacterial compound for drug repurposing against MDR Bacteria |
| Study Type | In vitro antibacterial studies |
| Study Summary | The current study re-defines a method to reveal bioactive compounds from the crude extracts of Malaysian red seaweed Gracilaria edulis, having promising antibacterial activities against selected bacterial species. Three species of Gram-positive and - negative characters were remarkably inhibited by the sequential and direct extracts of ethyl acetate and acetone. These were further separated through chromatographic methods to reveal a plethora of chemical constituents to be considered for a downstream virtual screening against selected crucial proteins of the six bacteria. |
| Institute | Sunway University |
| Department | Biological Sciences, Sunway University, Selangor, Malaysia |
| Laboratory | Disease Complexity |
| Last Name | Lahiri |
| First Name | Chandrajit |
| Address | Sunway University, No. 5, Jalan Universiti, Bandar Sunway, Petaling Jaya 47500, Selangor, Malaysia |
| chandrajitl@sunway.edu.my | |
| Phone | +60 3 7491 8622 |
| Submit Date | 2021-04-13 |
| Raw Data Available | Yes |
| Analysis Type Detail | LC-MS |
| Release Date | 2021-10-20 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Other organism; Subject species: Gracilaria edulis (Factor headings shown in green)
| mb_sample_id | local_sample_id | Solvent | Treatment |
|---|---|---|---|
| SA171097 | GE-GC-AC(d) | Acetone | Direct |
| SA171098 | GE-GC-AC(s) | Acetone | Sequential |
| SA171099 | GE-LC-AC(s) | Acetone | Sequential |
| SA171100 | BL-GC-AC(d) | Blank(Acetone) | Direct |
| SA171101 | BL-GC-AC(s) | Blank(Acetone) | Sequential |
| SA171102 | BL-GC-EA(d) | Blank(Ethyl acetate) | Direct |
| SA171103 | BL-GC-EA(s) | Blank(Ethyl acetate) | Sequential |
| SA171104 | BL-LC-MT(s) | Blank(Methanol) | Sequential |
| SA171105 | GE-GC-EA(d) | Ethyl acetate | Direct |
| SA171106 | GE-GC-EA(s) | Ethyl acetate | Sequential |
| SA171107 | GE-LC-EA(s) | Ethyl acetate | Sequential |
| Showing results 1 to 11 of 11 |
