Summary of Study ST001839
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001161. The data can be accessed directly via it's Project DOI: 10.21228/M8N11H This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001839 |
Study Title | Metabolite profiling of Malaysian Gracilaria edulis reveals Eplerenone as novel antibacterial compound for drug repurposing against MDR Bacteria |
Study Type | In vitro antibacterial studies |
Study Summary | The current study re-defines a method to reveal bioactive compounds from the crude extracts of Malaysian red seaweed Gracilaria edulis, having promising antibacterial activities against selected bacterial species. Three species of Gram-positive and - negative characters were remarkably inhibited by the sequential and direct extracts of ethyl acetate and acetone. These were further separated through chromatographic methods to reveal a plethora of chemical constituents to be considered for a downstream virtual screening against selected crucial proteins of the six bacteria. |
Institute | Sunway University |
Department | Biological Sciences, Sunway University, Selangor, Malaysia |
Laboratory | Disease Complexity |
Last Name | Lahiri |
First Name | Chandrajit |
Address | Sunway University, No. 5, Jalan Universiti, Bandar Sunway, Petaling Jaya 47500, Selangor, Malaysia |
chandrajitl@sunway.edu.my | |
Phone | +60 3 7491 8622 |
Submit Date | 2021-04-13 |
Raw Data Available | Yes |
Analysis Type Detail | LC-MS |
Release Date | 2021-10-20 |
Release Version | 1 |
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Collection:
Collection ID: | CO001909 |
Collection Summary: | Healthy specimens of Gracilaria edulis were collected from Pantai Morib, Selangor, Malaysia. Further, for the correct identification of G. edulis, observation of the characters was carried out according to Guiry & Guiry (2021). |
Sample Type: | Seaweed |