Summary of Study ST000166

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000144. The data can be accessed directly via it's Project DOI: 10.21228/M8C01P This work is supported by NIH grant, U2C- DK119886.


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Study IDST000166
Study TitleCardiac Resynchronization Therapy Induces Adaptive Metabolic Transitions in the Metabolomic Profile of Heart Failure
Study Typeintervention
Study SummaryThis prospective study consisted of 24 patients undergoing CRT for advanced HF and 10 control patients who underwent catheter ablation for supraventricular arrhythmia but not CRT. Blood samples were collected before and 3 months after CRT. Metabolomic profiling of plasma samples was performed using gas chromatography–mass spectrometry and nuclear magnetic resonance.
Mayo Clinic
DepartmentDepartment of Medicine
Last NameCha
First NameYong-Mei
Submit Date2015-05-14
Num Groups3
Total Subjects24
Raw Data AvailableNo
Raw Data File Type(s)d
Analysis Type DetailGC-MS
Release Date2015-06-28
Release Version1
Yong-Mei Cha Yong-Mei Cha application/zip

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Collection ID:CO000171
Collection Summary:Blood samples were taken from a peripheral vein. These blood samples (5 mL) were collected into EDTA tubes containing 100 ?L of injected stop solution (dipyrimidole,10 ?M; EHNA, 5 ?M; iodotubercidin, 2 ?M; AOPCP, 50 ?M, in 0.9% NaCl) to reduce blood nucleotide metabolism; stored on ice; and then centrifuged at 3,200 rpm for 10 minutes at 4°C. Plasma aliquots were stored at ?80°C until analyses.
Sample Type:Blood