Summary of Study ST001354
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000924. The data can be accessed directly via it's Project DOI: 10.21228/M8810Q This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001354 |
Study Title | 48 hours post-treatment L-Carnitine Pharmacometabolomics in Sepsis (CaPS) Patients |
Study Type | multiple timepoints; patients with severe sepsis or septic shock treated with varying doses of L-carnitine or a saline placebo |
Study Summary | phase II study of L-carnitine infusion for the treatment of vasopressor-dependent shock |
Institute | University of Michigan |
Department | Clinical Pharmacy |
Laboratory | Stringer NMR Metabolomics Laboratory |
Last Name | McHugh |
First Name | Cora |
Address | 428 Church St, Ann Arbor, MI, 48103, USA |
NMRmetabolomics@umich.edu | |
Phone | 7343530164 |
Submit Date | 2020-04-09 |
Num Groups | 4 |
Total Subjects | 228 |
Num Males | 128 |
Num Females | 100 |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Analysis Type Detail | NMR |
Release Date | 2020-07-05 |
Release Version | 1 |
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Collection:
Collection ID: | CO001423 |
Collection Summary: | Serum collected via existing intravenous or arterial catheter |
Collection Protocol Filename: | mchughce_20200409_121816_PR_CO_235.1_NMR_of_CAPS_RACE_Human_Sepsis_Serum.pdf mchughce_20200409_121816_PR_CO_Expt._235.1_Filtration_of_CaPS_RACE_Serums.pdf mchughce_20200409_121816_PR_CO_235.01-Serum_MeOH_Precip_and_Resuspension.pdf |
Collection Protocol Comments: | T0: collected before carnitine or placebo administration, T24: collected 24h after administration of L-carnitine or placebo (±4h), T48: collected 48h after administration of L-carnitine or placebo (±4h) |
Sample Type: | Blood (serum) |
Collection Method: | via existing intravenous or arterial catheter |
Collection Frequency: | 1/timepoint, 5 collections/72h |
Storage Conditions: | -80℃ |
Collection Vials: | SST: Becton-Dickinson 10mL vacutainer Serum Separator tubes |
Storage Vials: | Sterile 1mL cryovials |