Summary of Study ST001354

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000924. The data can be accessed directly via it's Project DOI: 10.21228/M8810Q This work is supported by NIH grant, U2C- DK119886.


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Study IDST001354
Study Title48 hours post-treatment L-Carnitine Pharmacometabolomics in Sepsis (CaPS) Patients
Study Typemultiple timepoints; patients with severe sepsis or septic shock treated with varying doses of L-carnitine or a saline placebo
Study Summaryphase II study of L-carnitine infusion for the treatment of vasopressor-dependent shock
University of Michigan
DepartmentClinical Pharmacy
LaboratoryStringer NMR Metabolomics Laboratory
Last NameMcHugh
First NameCora
Address428 Church St, Ann Arbor, MI, 48103, USA
Submit Date2020-04-09
Num Groups4
Total Subjects228
Num Males128
Num Females100
Raw Data AvailableYes
Raw Data File Type(s)fid
Analysis Type DetailNMR
Release Date2020-07-05
Release Version1
Cora McHugh Cora McHugh application/zip

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NMR ID:NM000163
Analysis ID:AN002253
Instrument Name:Varian 11.74T
Instrument Type:FT-NMR
NMR Experiment Type:1D-1H
NMR Comments:Arrayed for water saturation frequency and 90deg. pulse width for each sample. Varian (now Agilent, Inc., Santa Clara, CA) 11.74 Tesla (500 MHz) NMR spectrometer
Spectrometer Frequency:500 MHz
NMR Probe:5-mm Agilent “One-probe
NMR Solvent:D20
NMR Tube Size:5mm
Shimming Method:Auto shim (gradient shimming)
Pulse Sequence:1 H,1 H-NOESY (commonly referred to as a 1D-NOESY or METNOESY)
Water Suppression:saturation at 80 Hz induced field strength
Pulse Width:~5.5ms, arrayed for in each sample
Number Of Scans:32