Summary of Study ST002436
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001568. The data can be accessed directly via it's Project DOI: 10.21228/M8142B This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002436 |
| Study Title | Discovery of phytochelatins in human urine: Evidence for function in selenium disposition and protection against cadmium |
| Study Summary | The goal of this project was to detect phytochelatins, plant-derived peptides which function as metal chelators, in human urine. Untargeted metabolomics of 143 urine samples from healthy adults was performed. Phytochelatin 2, γE-C-γE-C-G, was detected, and the rest of the urine metabolome was searched for phytochelatins and predicted phytochelatin metabolites which correlated with phytochelatin 2 concentrations. Phytochelatin 2 and associated metabolites were found to correlate with urinary metals, and further experiments were performed provide insight into function of dietary phytochelatins. |
| Institute | Emory University |
| Last Name | Jarrell |
| First Name | Zachery |
| Address | 615 Michael St |
| zjarrel@emory.edu | |
| Phone | 4047275984 |
| Submit Date | 2023-01-10 |
| Total Subjects | 143 |
| Num Males | 37 |
| Num Females | 106 |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-01-25 |
| Release Version | 1 |
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Collection:
| Collection ID: | CO002518 |
| Collection Summary: | Samples were collected using standard operating procedures in the Center for Health Discovery and Well Being (CHDWB) cohort of healthy adults. The CHDWB enrolled 763 participants starting in 2008 with approval from the Emory Institutional Review Board (IRB approval No. 00007243). The original study included both genders and included individuals self-identifying as white, black, Hispanic and Asian. The present study selected available archival samples from 143 individuals without known disease. Urine samples included one sample per individual that was collected at either baseline, 6 months, or 12 months. Urine samples were stored at -80 ºC prior to analysis |
| Sample Type: | Urine |
