Summary of Study ST000254
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000206. The data can be accessed directly via it's Project DOI: 10.21228/M8RW2F This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
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| Study ID | ST000254 |
| Study Title | The role of microbial metabolites in experimental liver disease |
| Study Type | Targeted Metabolomic Analysis of plasma samples |
| Study Summary | Aim 1: Our experimental approach is to understand the effect of drinking water supplemented bacterial metabolite, Indole-3-propionic Acid (IPA), in liver disease in an acute alcohol model. Aim 2: Determine the levels of IPA in plasma of conventional mice in a chronic alcohol model. Aim 3: Determine the levels of IPA in plasma of conventional WT (C57BL/6) and mutant SL (sublytic, which is a mouse with a point mutation in ATP4a) mice. |
| Institute | University of North Carolina |
| Department | Discovery Science Technology |
| Laboratory | Sumner Lab |
| Last Name | Sumner |
| First Name | Susan |
| Address | Eastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081 |
| susan_sumner @unc.edu | |
| Phone | 704-250-5066 |
| Submit Date | 2015-09-29 |
| Num Groups | 2 |
| Total Subjects | 31 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | wiff |
| Uploaded File Size | 8.6 M |
| Analysis Type Detail | LC-MS |
| Release Date | 2016-12-22 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Animal; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | Groups | Treatment | Strain |
|---|---|---|---|---|
| SA011574 | P7 | Acute Alcohol Model | 0 mM IPA | WT |
| SA011575 | P8 | Acute Alcohol Model | 0 mM IPA | WT |
| SA011580 | P15 | Acute Alcohol Model | 10 mM IPA | WT |
| SA011581 | P14 | Acute Alcohol Model | 10 mM IPA | WT |
| SA011582 | P13 | Acute Alcohol Model | 10 mM IPA | WT |
| SA011576 | P10 | Acute Alcohol Model | 1 mM IPA | WT |
| SA011577 | P11 | Acute Alcohol Model | 1 mM IPA | WT |
| SA011578 | P12 | Acute Alcohol Model | 1 mM IPA | WT |
| SA011579 | P9 | Acute Alcohol Model | 1 mM IPA | WT |
| SA011583 | STD10 | Calibration Standard 10 | 2000 ng/ml of IPA | N/A |
| SA011584 | STD11 | Calibration Standard 11 | 2500 ng/ml of IPA | N/A |
| SA011585 | STD12 | Calibration Standard 12 | 3000 ng/ml of IPA | N/A |
| SA011586 | STD1 | Calibration Standard 1 | 10 ng/ml of IPA | N/A |
| SA011587 | STD2 | Calibration Standard 2 | 20 ng/ml of IPA | N/A |
| SA011588 | STD3 | Calibration Standard 3 | 40 ng/ml of IPA | N/A |
| SA011589 | STD4 | Calibration Standard 4 | 80 ng/ml of IPA | N/A |
| SA011590 | STD5 | Calibration Standard 5 | 160 ng/ml of IPA | N/A |
| SA011591 | STD6 | Calibration Standard 6 | 320 ng/ml of IPA | N/A |
| SA011592 | STD7 | Calibration Standard 7 | 650 ng/ml of IPA | N/A |
| SA011593 | STD8 | Calibration Standard 8 | 1000 ng/ml of IPA | N/A |
| SA011594 | STD9 | Calibration Standard 9 | 1500 ng/ml of IPA | N/A |
| SA011595 | P28 | Chronic Alcohol Model | No IPA | SL |
| SA011596 | P29 | Chronic Alcohol Model | No IPA | SL |
| SA011597 | P30 | Chronic Alcohol Model | No IPA | SL |
| SA011598 | P31 | Chronic Alcohol Model | No IPA | SL |
| SA011599 | P27 | Chronic Alcohol Model | No IPA | WT |
| SA011600 | P24 | Chronic Alcohol Model | No IPA | WT |
| SA011601 | P20 | Chronic Alcohol Model | No IPA | WT |
| SA011602 | P26 | Chronic Alcohol Model | No IPA | WT |
| SA011603 | P22 | Chronic Alcohol Model | No IPA | WT |
| SA011604 | P21 | Chronic Alcohol Model | No IPA | WT |
| SA011605 | P25 | Chronic Alcohol Model | No IPA | WT |
| SA011606 | P23 | Chronic Alcohol Model | No IPA | WT |
| SA011607 | P2 | Control | 0 mM IPA | WT |
| SA011608 | P1 | Control | 0 mM IPA | WT |
| SA011611 | P6 | Control | 10 mM IPA | WT |
| SA011612 | P5 | Control | 10 mM IPA | WT |
| SA011609 | P4 | Control | 1 mM IPA | WT |
| SA011610 | P3 | Control | 1 mM IPA | WT |
| SA011613 | P16 | Control | No IPA | WT |
| SA011614 | P19 | Control | No IPA | WT |
| SA011615 | P18 | Control | No IPA | WT |
| SA011616 | P17 | Control | No IPA | WT |
| SA011617 | QC1 | Quality Control Sample 1 | 30 ng/ml of IPA | N/A |
| SA011618 | QC2 | Quality Control Sample 2 | 200 ng/ml of IPA | N/A |
| SA011619 | QC3 | Quality Control Sample 3 | 600 ng/ml of IPA | N/A |
| SA011620 | QC4 | Quality Control Sample 4 | 1800 ng/ml of IPA | N/A |
| SA011621 | QC5 | Quality Control Sample 5 | 2400 ng/ml of IPA | N/A |
| Showing results 1 to 48 of 48 |
