Summary of Study ST000612

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000448. The data can be accessed directly via it's Project DOI: 10.21228/M84W37 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

Study ID	ST000612
Study Title	Sphingolipid Analysis of Human Aqueous Humor in Glaucomatous and Control eyes (part I)
Study Summary	This study examined the profiles of sphin¬golipids and ceramides present in the aqueous humor (AH) of human control and POAG donors. Furthermore, we quantitatively compared distinct differences between glaucomatous and age-matched control eyes, identifying potential molecules for further experimentation to determine their biological role in modulating cell behavior. Lipids were identified and ratiometrically quantified in a two-step process using precursor ion scan (PIS) or neutral loss scan (NLS) with appropriate class-specific lipid standards on a TSQ Quantum Access Max mass spectrometer following established procedures. We identified several species of sphingomyelin, sphingoid base, sphingoid base-1-phosphate, and ceramides that were common between control and glaucomatous AQH. Some unique lipid species in these classes were also identified in controls but not in glaucoma and vice versa.
Institute	University of Miami
Last Name	Bhattacharya
First Name	Sanjoy
Address	1638 NW 10th Avenue, Miami, Florida, 33136, USA
Email	sbhattacharya@med.miami.edu
Phone	3054824103
Submit Date	2017-05-26
Raw Data Available	Yes
Raw Data File Type(s)	raw(Thermo)
Analysis Type Detail	MS(Dir. Inf.)
Release Date	2019-07-17
Release Version	1

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id	local_sample_id	Condition
SA033857	NAH16BL3	Control
SA033858	NAH14BL3	Control
SA033859	NAH13BL3	Control
SA033860	NAH17BL2	Control
SA033861	NAH19BL3	Control
SA033862	NAH1BL3	Control
SA033863	NAH20BL3	Control
SA033864	NAH12BL3	Control
SA033865	NAH18BL2	Control
SA033866	NAH15BL3	Control
SA033867	NAH5BL3	Control
SA033868	NAH4BL3	Control
SA033869	NAH11BL4	Control
SA033870	NAH2BL3	Control
SA033871	NAH6BL3	Control
SA033872	NAH3BL3	Control
SA033873	NAH7BL4	Control
SA033874	NAH10BL3	Control
SA033875	NAH9BL3	Control
SA033876	NAH8BL3	Control
SA033877	GAH15BL3	Glaucomatous
SA033878	GAH14BL3	Glaucomatous
SA033879	GAH13BL3	Glaucomatous
SA033880	GAH16BL3	Glaucomatous
SA033881	GAH19BL3	Glaucomatous
SA033882	GAH12BL3	Glaucomatous
SA033883	GAH20BL3	Glaucomatous
SA033884	GAH18BL3	Glaucomatous
SA033885	GAH17BL4	Glaucomatous
SA033886	GAH1BL3	Glaucomatous
SA033887	GAH5BL3	Glaucomatous
SA033888	GAH4BL3	Glaucomatous
SA033889	GAH3BL3	Glaucomatous
SA033890	GAH2BL3	Glaucomatous
SA033891	GAH6BL3	Glaucomatous
SA033892	GAH7BL4	Glaucomatous
SA033893	GAH10BL3	Glaucomatous
SA033894	GAH9BL3	Glaucomatous
SA033895	GAH8BL3	Glaucomatous
SA033896	GAH11BL3	Glaucomatous

Showing results 1 to 40 of 40

Showing results 1 to 40 of 40