Summary of Study ST002432

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001565. The data can be accessed directly via it's Project DOI: 10.21228/M8DD8S This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002432
Study TitleMetabolic impacts of metformin to seasonal influenza vaccination: a pilot study of drug interaction with the immune response
Study SummaryWe report here a double-blinded pilot study of seasonal influenza vaccination, where half of the participants received daily metformin administration. Global metabolomics was measured in the plasma samples at six timepoints. Metformin signatures were successfully identified in the metabolomics data. Statistically significant metabolite features were found both for the vaccination effect and for the drug-vaccine interactions.
Institute
The Jackson Laboratory for Genomic Medicine
LaboratoryShuzhao Li Lab
Last NameSiddiqa
First NameAmnah
Address10 Discovery dr, Farmington, CT 06032
Emailamnah.siddiqa@jax.org
Phone4049187223
Submit Date2023-01-04
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2023-01-20
Release Version1
Amnah Siddiqa Amnah Siddiqa
https://dx.doi.org/10.21228/M8DD8S
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Visit Treatment
SA242997YW_20201206_163.mzMLV1 Metformin
SA242998YW_20201206_135.mzMLV1 Metformin
SA242999YW_20201206_101.mzMLV1 Metformin
SA243000YW_20201206_227.mzMLV1 Metformin
SA243001YW_20201206_072.mzMLV1 Metformin
SA243002YW_20201206_089.mzMLV1 Metformin
SA243003YW_20201206_199.mzMLV1 Metformin
SA243004YW_20201206_071.mzMLV1 Metformin
SA243005YW_20201210_163.mzMLV1 Metformin
SA243006YW_20201210_135.mzMLV1 Metformin
SA243007YW_20201210_199.mzMLV1 Metformin
SA243008YW_20201210_227.mzMLV1 Metformin
SA243009YW_20201206_115.mzMLV1 Metformin
SA243010YW_20201206_090.mzMLV1 Metformin
SA243011YW_20201206_136.mzMLV1 Metformin
SA243012YW_20201210_164.mzMLV1 Metformin
SA243013YW_20201210_136.mzMLV1 Metformin
SA243014YW_20201210_102.mzMLV1 Metformin
SA243015YW_20201210_200.mzMLV1 Metformin
SA243016YW_20201210_228.mzMLV1 Metformin
SA243017YW_20201210_090.mzMLV1 Metformin
SA243018YW_20201210_072.mzMLV1 Metformin
SA243019YW_20201206_102.mzMLV1 Metformin
SA243020YW_20201206_164.mzMLV1 Metformin
SA243021YW_20201206_200.mzMLV1 Metformin
SA243022YW_20201206_228.mzMLV1 Metformin
SA243023YW_20201210_116.mzMLV1 Metformin
SA243024YW_20201210_115.mzMLV1 Metformin
SA243025YW_20201206_116.mzMLV1 Metformin
SA243026YW_20201210_101.mzMLV1 Metformin
SA243027YW_20201210_089.mzMLV1 Metformin
SA243028YW_20201210_071.mzMLV1 Metformin
SA243029YW_20201210_174.mzMLV1 Placebo
SA243030YW_20201210_038.mzMLV1 Placebo
SA243031YW_20201210_173.mzMLV1 Placebo
SA243032YW_20201210_194.mzMLV1 Placebo
SA243033YW_20201206_193.mzMLV1 Placebo
SA243034YW_20201206_245.mzMLV1 Placebo
SA243035YW_20201210_246.mzMLV1 Placebo
SA243036YW_20201206_235.mzMLV1 Placebo
SA243037YW_20201210_236.mzMLV1 Placebo
SA243038YW_20201206_037_20201208155945.mzMLV1 Placebo
SA243039YW_20201210_245.mzMLV1 Placebo
SA243040YW_20201210_235.mzMLV1 Placebo
SA243041YW_20201206_173.mzMLV1 Placebo
SA243042YW_20201206_140.mzMLV1 Placebo
SA243043YW_20201210_058.mzMLV1 Placebo
SA243044YW_20201210_037.mzMLV1 Placebo
SA243045YW_20201210_193.mzMLV1 Placebo
SA243046YW_20201206_057.mzMLV1 Placebo
SA243047YW_20201210_057.mzMLV1 Placebo
SA243048YW_20201206_139.mzMLV1 Placebo
SA243049YW_20201210_139.mzMLV1 Placebo
SA243050YW_20201206_058.mzMLV1 Placebo
SA243051YW_20201210_140.mzMLV1 Placebo
SA243052YW_20201206_174.mzMLV1 Placebo
SA243053YW_20201206_194.mzMLV1 Placebo
SA243054YW_20201206_038_20201208160505.mzMLV1 Placebo
SA243055YW_20201206_246.mzMLV1 Placebo
SA243056YW_20201206_236.mzMLV1 Placebo
SA243057YW_20201206_220.mzMLV2 Metformin
SA243058YW_20201210_087.mzMLV2 Metformin
SA243059YW_20201206_088.mzMLV2 Metformin
SA243060YW_20201210_158.mzMLV2 Metformin
SA243061YW_20201206_067.mzMLV2 Metformin
SA243062YW_20201206_158.mzMLV2 Metformin
SA243063YW_20201206_107_20201210165216.mzMLV2 Metformin
SA243064YW_20201210_094.mzMLV2 Metformin
SA243065YW_20201206_087.mzMLV2 Metformin
SA243066YW_20201206_208.mzMLV2 Metformin
SA243067YW_20201206_134.mzMLV2 Metformin
SA243068YW_20201210_067.mzMLV2 Metformin
SA243069YW_20201206_219.mzMLV2 Metformin
SA243070YW_20201210_107.mzMLV2 Metformin
SA243071YW_20201210_093.mzMLV2 Metformin
SA243072YW_20201210_108.mzMLV2 Metformin
SA243073YW_20201206_108_20201210165738.mzMLV2 Metformin
SA243074YW_20201206_207.mzMLV2 Metformin
SA243075YW_20201206_093.mzMLV2 Metformin
SA243076YW_20201210_088.mzMLV2 Metformin
SA243077YW_20201206_133.mzMLV2 Metformin
SA243078YW_20201206_094.mzMLV2 Metformin
SA243079YW_20201210_068.mzMLV2 Metformin
SA243080YW_20201206_068.mzMLV2 Metformin
SA243081YW_20201210_134.mzMLV2 Metformin
SA243082YW_20201206_157.mzMLV2 Metformin
SA243083YW_20201210_220.mzMLV2 Metformin
SA243084YW_20201210_219.mzMLV2 Metformin
SA243085YW_20201210_133.mzMLV2 Metformin
SA243086YW_20201210_157.mzMLV2 Metformin
SA243087YW_20201210_208.mzMLV2 Metformin
SA243088YW_20201210_207.mzMLV2 Metformin
SA243089YW_20201206_248.mzMLV2 Placebo
SA243090YW_20201210_191.mzMLV2 Placebo
SA243091YW_20201210_192.mzMLV2 Placebo
SA243092YW_20201210_043.mzMLV2 Placebo
SA243093YW_20201210_044.mzMLV2 Placebo
SA243094YW_20201206_182.mzMLV2 Placebo
SA243095YW_20201210_182.mzMLV2 Placebo
SA243096YW_20201210_142.mzMLV2 Placebo
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