Summary of Study ST002432
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001565. The data can be accessed directly via it's Project DOI: 10.21228/M8DD8S This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002432 |
| Study Title | Metabolic impacts of metformin to seasonal influenza vaccination: a pilot study of drug interaction with the immune response |
| Study Summary | We report here a double-blinded pilot study of seasonal influenza vaccination, where half of the participants received daily metformin administration. Global metabolomics was measured in the plasma samples at six timepoints. Metformin signatures were successfully identified in the metabolomics data. Statistically significant metabolite features were found both for the vaccination effect and for the drug-vaccine interactions. |
| Institute | The Jackson Laboratory for Genomic Medicine |
| Laboratory | Shuzhao Li Lab |
| Last Name | Siddiqa |
| First Name | Amnah |
| Address | 10 Discovery dr, Farmington, CT 06032 |
| amnah.siddiqa@jax.org | |
| Phone | 4049187223 |
| Submit Date | 2023-01-04 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzML |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-01-20 |
| Release Version | 1 |
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Project:
| Project ID: | PR001565 |
| Project DOI: | doi: 10.21228/M8DD8S |
| Project Title: | Metabolic impacts of metformin to seasonal influenza vaccination: a pilot study of drug interaction with the immune response |
| Project Summary: | We report here a double-blinded pilot study of seasonal influenza vaccination, where half of the participants received daily metformin administration. Global metabolomics was measured in the plasma samples at six timepoints. Metformin signatures were successfully identified in the metabolomics data. Statistically significant metabolite features were found both for the vaccination effect and for the drug-vaccine interactions. |
| Institute: | The Jackson Laboratory For Genomic Medicine |
| Laboratory: | Shuzhao Li Lab |
| Last Name: | Siddiqa |
| First Name: | Amnah |
| Address: | 10 Discovery Drive , Farmington, CT 06032 |
| Email: | amnah.siddiqa@jax.org |
| Phone: | 4049187223 |
