Summary of Study ST000590
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000431. The data can be accessed directly via it's Project DOI: 10.21228/M8BK5R This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST000590 |
| Study Title | Human Plasma Metabolomics in Age-related Macular Degeneration (AMD) Using Nuclear Magnetic Resonance Spectroscopy |
| Study Type | Observational, cross-sectional, multi-site study, NMR metabolomics |
| Study Summary | Multi-site, cross-sectional study, including subjects with Age-related Macular Degeneration (early, intermediate and late disease) and a control group of subjects without any macular diseases. Plasma metabolomic profiles were assessed using Nuclear Magnetic Resonance Spectroscopy (NMR). Multivariate statistics were performed to compare metabolomic profiles of AMD patients vs controls. |
| Institute | University of Aveiro |
| Department | Department of Chemistry and CICECO_Aveiro Institute of Materials |
| Laboratory | University of Aveiro |
| Last Name | Gil |
| First Name | Ana |
| Address | Campus de Santiago, Aveiro, Aveiro, 3810-193, Portugal |
| agil@ua.pt | |
| Phone | +351234370707 |
| Submit Date | 2017-02-20 |
| Num Groups | 4 |
| Total Subjects | 396 |
| Num Males | 143 |
| Num Females | 253 |
| Analysis Type Detail | NMR |
| Release Date | 2017-07-10 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
NMR:
| NMR ID: | NM000102 |
| Analysis ID: | AN000905 |
| Instrument Name: | Bruker Avance DRX 500 spectrometer |
| Instrument Type: | FT-NMR |
| NMR Experiment Type: | 1D 1H |
| Spectrometer Frequency: | 500 MHz |
| NMR Probe: | TXI |
| NMR Solvent: | H2O+D2O (10%)_salt |
| NMR Tube Size: | 5 mm |
| Shimming Method: | Automated |
| Pulse Sequence: | cpmgpr1d and ledbpgp2s1dpr |
| Water Suppression: | Yes |
| Pulse Width: | 7 us |
| Receiver Gain: | 128 and 203 |
| Chemical Shift Ref Cpd: | glucose |
| Temperature: | 300 K |
| Number Of Scans: | 256 and 128 |
| Dummy Scans: | 4 |
| Acquisition Time: | 1.59 s |
| Relaxation Delay: | 4 s |
| Spectral Width: | 20,6557 Hz |
| Num Data Points Acquired: | 32 k |
| Real Data Points: | 32 k |
| Line Broadening: | 0,3 Hz |
| Zero Filling: | 64 k |
| Baseline Correction Method: | manual |
| Chemical Shift Ref Std: | glucose (5.23 ppm) |
| Binned Increment: | full resolution |
| Binned Data Excluded Range: | 4.50-5.15 ppm |
