Summary of Study ST000590
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000431. The data can be accessed directly via it's Project DOI: 10.21228/M8BK5R This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST000590 |
| Study Title | Human Plasma Metabolomics in Age-related Macular Degeneration (AMD) Using Nuclear Magnetic Resonance Spectroscopy |
| Study Type | Observational, cross-sectional, multi-site study, NMR metabolomics |
| Study Summary | Multi-site, cross-sectional study, including subjects with Age-related Macular Degeneration (early, intermediate and late disease) and a control group of subjects without any macular diseases. Plasma metabolomic profiles were assessed using Nuclear Magnetic Resonance Spectroscopy (NMR). Multivariate statistics were performed to compare metabolomic profiles of AMD patients vs controls. |
| Institute | University of Aveiro |
| Department | Department of Chemistry and CICECO_Aveiro Institute of Materials |
| Laboratory | University of Aveiro |
| Last Name | Gil |
| First Name | Ana |
| Address | Campus de Santiago, Aveiro, Aveiro, 3810-193, Portugal |
| agil@ua.pt | |
| Phone | +351234370707 |
| Submit Date | 2017-02-20 |
| Num Groups | 4 |
| Total Subjects | 396 |
| Num Males | 143 |
| Num Females | 253 |
| Analysis Type Detail | NMR |
| Release Date | 2017-07-10 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Subject:
| Subject ID: | SU000613 |
| Subject Type: | HUman |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Age Or Age Range: | 51-95 |
| Gender: | 253 female; 143 male |
| Human Smoking Status: | 5 smokers; 113 ex-smokers; 275 non smokers |
| Human Inclusion Criteria: | For AMD group: clinical diagnosis of AMD, confirmed on color fundus photographs; For controls: age equal or superior than 50 years old, with normal macular health |
| Human Exclusion Criteria: | Diagnosis of any other vitreoretinal disease, active uveitis or ocular infection, significant media opacities that precluded the observation of the ocular fundus, refractive error equal or greater than 6 diopters of spherical equivalent, past history of retinal surgery, history of any ocular surgery or intra-ocular procedure (such as laser and intra-ocular injections) within the 90 days prior to enrolment, and diagnosis of diabetes mellitus, with or without concomitant diabetic retinopathy. |
| Species Group: | Human |
