Summary of Study ST001911
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001205. The data can be accessed directly via it's Project DOI: 10.21228/M8Z700 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001911 |
| Study Title | A high-fat diet induced obesity murine model treated with bitter melon (Momordica charantia) |
| Study Type | A 40-day Intervention experiment |
| Study Summary | Metabolic effects of lyophilized bitter melon juice (BMJ) extract (oral gavage 200mg/kg/body weight-daily for 40 days) intake were evaluated in diet-induced obese C57BL/6J male mice [fed-high fat diet (HFD), 60 kcal% fat]. Changes in metabolite abundance levels in lipid-phase plasma [liquid chromatography mass spectrometry (LC-MS)-based metabolomics] after BMJ intervention were assessed. |
| Institute | University of Colorado Anschutz Medical Campus |
| Department | Pharmaceutical Sciences |
| Laboratory | Dr. Rajesh Agarwal's Laboratory |
| Last Name | Agarwal |
| First Name | Rajesh |
| Address | 12850 E. Montview Blvd, C238, Room V20-2118, Aurora, CO 80045, USA |
| Rajesh.Agarwal@cuanschutz.edu | |
| Phone | 303-724-4055 |
| Submit Date | 2021-05-22 |
| Num Groups | 2 |
| Total Subjects | 8 |
| Num Males | 8 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2021-08-30 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
| Project ID: | PR001205 |
| Project DOI: | doi: 10.21228/M8Z700 |
| Project Title: | Metabolome changes induced by bitter melon (Momordica charantia)- intake in a high-fat diet induced obesity model |
| Project Type: | LCMS quanitative analysis |
| Project Summary: | Quanitative analysis of metabolomics on samples from murine samples (KEGG Pathway MAPS, LIPIDMAPS, Human Metabolome Database) |
| Institute: | University of Colorado Anschutz Medical Campus |
| Department: | Pharmaceutical Sciences |
| Laboratory: | Dr. Rajesh Agarwal's Laboratory and |
| Last Name: | Agarwal |
| First Name: | Rajesh |
| Address: | 12850 E. Montview Blvd, C238, Room V20-2118, Aurora, CO 80045, USA |
| Email: | Rajesh.Agarwal@cuanschutz.edu |
| Phone: | 303-724-4055 |
| Funding Source: | This work was supported by the National Institutes of Health/ National Cancer Institute grant R01CA195708, the National Institutes of Health Office of Dietary Supplements supplemental funds R01CA195708-02S1, and the pilot funding from the office of the Associate Dean for Research and Graduate Education (ADR), School of Pharmacy, UC AMC (to RA), and the National Cancer Institute diversity supplement grant R01CA195708-04S1 (to DR and RA). |
| Contributors: | Dominique Reed, Dileep Kumar, Sushil Kumar, Komal Raina, Reenu Punia, Rama Kant, Laura Saba, Charmion Cruickshank-Quinn, Boris Tabakoff, Nichole Reisdorph, Michael G. Edwards, Michael Wempe, Chapla Agarwal, Rajesh Agarwal |
