Summary of Study ST001824
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001153. The data can be accessed directly via it's Project DOI: 10.21228/M8P10F This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001824 |
| Study Title | Metabolomic and lipidomic profiles of CKD in obese patients in serum and urine (part 1 of 3) |
| Study Type | Human nephropathy in CKD obese patients |
| Study Summary | Obesity is a global pandemic with an increase prevalence over the years. This condition elevates the risk of developing cardiovascular diseases, hypertension and renal pathologies, like chronic kidney disease (CKD). In the present study, the metabolomic and the lipidomic profiles of CKD obese patients were analyzed comparing with obese subjects without CKD. Subsequently, CKD obese patients underwent bariatric surgery and the effect of surgery in the CKD progression of these subjects was evaluated. Serum and urine were measured by LC-MS and GC-HRAM equipment. |
| Institute | University Rey Juan Carlos |
| Department | Basics Science of Health |
| Last Name | Lanzon |
| First Name | Borja |
| Address | Avenida de Atenas S/N |
| borja.lanzon@urjc.es | |
| Phone | 663692554 |
| Submit Date | 2021-04-02 |
| Num Groups | 3 |
| Total Subjects | 36 |
| Study Comments | Serum LC-MS data: part 1 of 3. Samples were analyzed per duplicated. |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2021-06-14 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Sample Preparation:
| Sampleprep ID: | SP001907 |
| Sampleprep Summary: | 10 µl of each serum sample were added to 10 µl of 0.9% NaCl and 120 µl of CHCl3: MeOH (2:1, v/v) containing a 2.5 ppm solution of different lipids standards. Samples were randomized, vortex-mixed and put on ice for 30 min. After that, samples were centrifuged (9400 g, 3 min, 4 °C). Then, 60 µl of the lower layer of each sample was transferred to a glass vial with an insert and 60 µl of CHCl3: MeOH (2:1, v/v) was added. Samples were stored at -80 °C until LC-MS analysis. |
| Processing Storage Conditions: | On ice |
| Extract Storage: | -80℃ |
