Studies involving disease:Alzheimers disease
| Study ID | Study Title | Species | Institute |
|---|---|---|---|
| ST000046 | Identification of altered metabolic pathways in Alzheimer's disease, mild cognitive impairment and cognitively normals using Metabolomics (plasma) | Human | Mayo Clinic |
| ST000047 | Identification of altered metabolic pathways in Alzheimer's disease, mild cognitive impairment and cognitively normals using Metabolomics (CSF) | Human | Mayo Clinic |
| ST000433 | Plasma sphingolipid changes with autopsy-confirmed Lewy body or Alzheimer's pathology | Human | Mayo Clinic |
| ST000462 | CNS and peripheral metabolomics of calorie restriction in a mouse model of Alzheimer’s disease (part I) | Mouse | University of North Carolina |
| ST000463 | CNS and peripheral metabolomics of calorie restriction in a mouse model of Alzheimer’s disease (part II) | Mouse | University of North Carolina |
| ST001749 | REACH Metabolomics Study | Human | University of Wisconsin-Madison |
| ST001819 | EC and PVC from 14-15 month-old APOE3/3, APOE3/4 and APOE4/4 mice | Mouse | Columbia University |
| ST001820 | WT neurons treated with APOE3/3 and APOE4/4 ACM | Mouse | Columbia University |
| ST001848 | Untargeted mass spectrometry reveals impact of high fat diet on peripheral amino acid regulation in a mouse model of Alzheimer’s Disease | Mouse | Vanderbilt University |
| ST002213 | Metabolic changes in Alzheimer patient-derived induced neurons versus non-demented controls | Human | University of Colorado Denver |
| ST002214 | The effects of PKM2 modulation and hypoxia on the metabolic landscape of Alzheimer patient-derived induced neurons | Human | University of Colorado Denver |
| ST002334 | Phospholipase D3 impact on the endolysosomal lipidome | Human | VIB-KU Leuven |
| ST003176 | Chronic manganese exposure disrupts glutamatergic signaling and alters behavior in APP/PSEN1 mice. | Mouse | Vanderbilt University |
| ST003215 | Protein restriction slows the development and progression of Alzheimer's disease in mice | Mouse | University of Wisconsin-Madison |
| ST003237 | Plasma metabolomics of patients diagnosed with Alzheimer's Disease under Acetylcholinesterase Inhibitors treatment | Human | University of Campinas |
| ST003249 | Mitochondrial respiration impairment in microglia dampens response to demyelinating injury but is not sufficient to induce an aging phenotype | Mouse | Northwestern University |
| ST003501 | TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism | Mouse | Denali Therapeutics |
| ST003737 | PILRA regulates microglial neuroinflammation and lipid metabolism as a candidate therapeutic target for Alzheimer’s disease | Human | Denali Therapeutics |
| ST003769 | Characterization of brain‐derived extracellular vesicle lipids in Alzheimer's disease | Human | University of Melbourne |
| ST003972 | Lipid cargo profiling of human brain-derived extracellular vesicles by APOE genotype in Alzheimer’s Disease | Human | Mayo Clinic |
| ST004057 | Microglial and Non-Microglial Regulation of Lipid Metabolism in Alzheimer's Revealed by Genetic and Pharmacological Depletion | Human | UT Health San Antonio |
| ST004057 | Microglial and Non-Microglial Regulation of Lipid Metabolism in Alzheimer's Revealed by Genetic and Pharmacological Depletion | Mouse | UT Health San Antonio |
| ST004168 | Integrative brain omics approach highlights sn-1 lysophosphatidylethanolamine in Alzheimer's dementia | Human | Emory University |
| ST004223 | Sulfatide deficiency-induced astrogliosis and myelin lipid dyshomeostasis are independent of Trem2-mediated microglial activation | Mouse | UT Health San Antonio |
| ST004230 | Effect of ATV:4D9 on Microglial Metabolism and FDG levels in mKate-TREM2/APP mouse model | Mouse | Denali Therapeutics |
| ST004287 | Lipidomic profiling of PILRAKO xMG in xenotransplant model after mouse microglia(mMg) depletion | Human | Denali Therapeutics |
