MGP Database

MGP000073

Ontology/Pathway Information

Entrez Gene ID	133
Gene Name	adrenomedullin
Gene Symbol	ADM
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005737	IDA:BHF-UCL	C	cytoplasm
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	IDA:BHF-UCL	C	extracellular space
GO:0005102	TAS:ProtInc	F	receptor binding
GO:0007568	IEA:Ensembl	P	aging
GO:0008209	IEA:Ensembl	P	androgen metabolic process
GO:0008015	TAS:ProtInc	P	blood circulation
GO:0060670	IEA:Ensembl	P	branching involved in labyrinthine layer morphogenesis
GO:0006171	IDA:UniProtKB	P	cAMP biosynthetic process
GO:0019933	IEA:Ensembl	P	cAMP-mediated signaling
GO:0007267	TAS:ProtInc	P	cell-cell signaling
GO:0048589	IEA:Ensembl	P	developmental growth
GO:0007565	TAS:ProtInc	P	female pregnancy
GO:0002031	IDA:UniProtKB	P	G-protein coupled receptor internalization
GO:0007507	IEA:Ensembl	P	heart development
GO:0046879	IEA:Ensembl	P	hormone secretion
GO:0008285	IEA:Ensembl	P	negative regulation of cell proliferation
GO:0043116	IEA:Ensembl	P	negative regulation of vascular permeability
GO:0045906	IDA:BHF-UCL	P	negative regulation of vasoconstriction
GO:0001843	IEA:Ensembl	P	neural tube closure
GO:0031102	IEA:Ensembl	P	neuron projection regeneration
GO:0042475	IEA:Ensembl	P	odontogenesis of dentin-containing tooth
GO:0031100	IEA:Ensembl	P	organ regeneration
GO:0045766	IEA:Ensembl	P	positive regulation of angiogenesis
GO:0043065	IEA:Ensembl	P	positive regulation of apoptotic process
GO:0030819	IDA:UniProtKB	P	positive regulation of cAMP biosynthetic process
GO:0008284	IEA:Ensembl	P	positive regulation of cell proliferation
GO:0007204	IEA:Ensembl	P	positive regulation of cytosolic calcium ion concentration
GO:0010460	IEA:Ensembl	P	positive regulation of heart rate
GO:2001214	IEA:Ensembl	P	positive regulation of vasculogenesis
GO:0045909	IEA:Ensembl	P	positive regulation of vasodilation
GO:0006701	TAS:ProtInc	P	progesterone biosynthetic process
GO:0031623	IDA:UniProtKB	P	receptor internalization
GO:0002026	IEA:Ensembl	P	regulation of the force of heart contraction
GO:0009409	IEA:Ensembl	P	response to cold
GO:0051384	IEA:Ensembl	P	response to glucocorticoid
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0032868	IEA:Ensembl	P	response to insulin
GO:0032496	IEA:Ensembl	P	response to lipopolysaccharide
GO:0042594	IEA:Ensembl	P	response to starvation
GO:0009611	TAS:ProtInc	P	response to wounding
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0060712	IEA:Ensembl	P	spongiotrophoblast layer development
GO:0097084	IEA:Ensembl	P	vascular smooth muscle cell development
GO:0001570	IDA:UniProtKB	P	vasculogenesis

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_18290	Calcitonin-like ligand receptors
REACT_18372	Class B/2 (Secretin family receptors)
REACT_267874	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125	Disease
REACT_19327	G alpha (s) signalling events
REACT_19184	GPCR downstream signaling
REACT_21340	GPCR ligand binding
REACT_267615	Metabolic disorders of biological oxidation enzymes
REACT_14797	Signaling by GPCR
REACT_111102	Signal Transduction