MGP Database

MGP000080

Ontology/Pathway Information

Entrez Gene ID	147
Gene Name	adrenoceptor alpha 1B
Gene Symbol	ADRA1B
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005887	TAS:ProtInc	C	integral component of plasma membrane
GO:0031965	IDA:UniProtKB	C	nuclear membrane
GO:0005634	IDA:UniProtKB	C	nucleus
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0004937	TAS:ProtInc	F	alpha1-adrenergic receptor activity
GO:0046982	IDA:UniProtKB	F	protein heterodimerization activity
GO:0007188	TAS:ProtInc	P	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0071875	TAS:GOC	P	adrenergic receptor signaling pathway
GO:0007512	IEA:Ensembl	P	adult heart development
GO:0048148	IEA:Ensembl	P	behavioral response to cocaine
GO:0001974	IEA:Ensembl	P	blood vessel remodeling
GO:0007267	TAS:ProtInc	P	cell-cell signaling
GO:0016049	IEA:Ensembl	P	cell growth
GO:0008283	TAS:ProtInc	P	cell proliferation
GO:0042593	IEA:Ensembl	P	glucose homeostasis
GO:0007186	TAS:ProtInc	P	G-protein coupled receptor signaling pathway
GO:0035556	TAS:ProtInc	P	intracellular signal transduction
GO:0007626	IEA:Ensembl	P	locomotory behavior
GO:0007275	TAS:ProtInc	P	multicellular organismal development
GO:0045818	IEA:Ensembl	P	negative regulation of glycogen catabolic process
GO:0035265	IEA:Ensembl	P	organ growth
GO:0045819	IEA:Ensembl	P	positive regulation of glycogen catabolic process
GO:0001996	IEA:Ensembl	P	positive regulation of heart rate by epinephrine-norepinephrine
GO:0043410	IDA:UniProtKB	P	positive regulation of MAPK cascade
GO:0001997	IEA:Ensembl	P	positive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0055117	IEA:InterPro	P	regulation of cardiac muscle contraction
GO:0019229	IEA:InterPro	P	regulation of vasoconstriction
GO:0001975	IEA:Ensembl	P	response to amphetamine
GO:0043278	IEA:Ensembl	P	response to morphine
GO:0001987	IEA:Ensembl	P	vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure
GO:0008542	IEA:Ensembl	P	visual learning

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_16927	Adrenoceptors
REACT_16983	Amine ligand-binding receptors
REACT_14828	Class A/1 (Rhodopsin-like receptors)
REACT_267874	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125	Disease
REACT_18407	G alpha (12/13) signalling events
REACT_18283	G alpha (q) signalling events
REACT_120966	Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184	GPCR downstream signaling
REACT_21340	GPCR ligand binding
REACT_267615	Metabolic disorders of biological oxidation enzymes
REACT_14797	Signaling by GPCR
REACT_111102	Signal Transduction