MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000127

Ontology/Pathway Information

Entrez Gene ID231
Gene Namealdo-keto reductase family 1, member B1 (aldose reductase)
Gene Symbol AKR1B1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005615 TAS:ProtIncCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005654 IDA:HPACnucleoplasm
GO:0004032 TAS:ProtIncFalditol:NADP+ 1-oxidoreductase activity
GO:0004033 TAS:UniProtKBFaldo-keto reductase (NADP) activity
GO:0009055 TAS:UniProtKBFelectron carrier activity
GO:0043795 IDA:UniProtKBFglyceraldehyde oxidoreductase activity
GO:0006700 TAS:ReactomePC21-steroid hormone biosynthetic process
GO:0005975 TAS:ProtIncPcarbohydrate metabolic process
GO:0044597 IMP:UniProtKBPdaunorubicin metabolic process
GO:0044598 IMP:UniProtKBPdoxorubicin metabolic process
GO:0006950 TAS:UniProtKBPresponse to stress
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0008202 TAS:ReactomePsteroid metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_11057Metabolism of steroid hormones and vitamin D
REACT_11038Pregnenolone biosynthesis
SMP Pathway Links
SMP IDDescription
SMP00529D-glyceric acidura
SMP00486Dopa-responsive dystonia
SMP00530Familial lipoprotein lipase deficiency
SMP00064Fructose and Mannose Degradation
SMP00725Fructose intolerance, hereditary
SMP00561Fructosuria
SMP00043Galactose Metabolism
SMP00182Galactosemia
SMP00039Glycerolipid Metabolism
SMP00187Glycerol Kinase Deficiency
SMP00487Hyperphenylalaniemia due to guanosine triphosphate cyclohydrolase deficiency
SMP00488Hyperphenylalaninemia due to 6-pyruvoyltetrahydropterin synthase deficiency (ptps)
SMP00489Hyperphenylalaninemia due to dhpr-deficiency
SMP00196Leigh Syndrome
SMP00558Primary hyperoxaluria II, PH2
SMP00005Pterine Biosynthesis
SMP00334Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)
SMP00212Pyruvate Dehydrogenase Complex Deficiency
SMP00559Pyruvate kinase deficiency
SMP00060Pyruvate Metabolism
SMP00490Segawa syndrome
SMP00491Sepiapterin reductase deficiency
  logo