MGP Database

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MGP000173

Ontology/Pathway Information

Entrez Gene ID345
Gene Nameapolipoprotein C-III
Gene Symbol APOC3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0042627 IDA:BHF-UCLCchylomicron
GO:0005769 TAS:ReactomeCearly endosome
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0034363 IDA:BHF-UCLCintermediate-density lipoprotein particle
GO:0034366 IDA:BHF-UCLCspherical high-density lipoprotein particle
GO:0034361 IDA:BHF-UCLCvery-low-density lipoprotein particle
GO:0015485 IC:BHF-UCLFcholesterol binding
GO:0030234 IDA:BHF-UCLFenzyme regulator activity
GO:0070653 IPI:BHF-UCLFhigh-density lipoprotein particle receptor binding
GO:0055102 IDA:BHF-UCLFlipase inhibitor activity
GO:0005543 IDA:BHF-UCLFphospholipid binding
GO:0071333 IEA:EnsemblPcellular response to glucose stimulus
GO:0033344 IDA:BHF-UCLPcholesterol efflux
GO:0042632 IMP:BHF-UCLPcholesterol homeostasis
GO:0008203 IEA:EnsemblPcholesterol metabolic process
GO:0034382 IDA:BHF-UCLPchylomicron remnant clearance
GO:0007186 IDA:BHF-UCLPG-protein coupled receptor signaling pathway
GO:0034375 IMP:BHF-UCLPhigh-density lipoprotein particle remodeling
GO:0006954 IEA:EnsemblPinflammatory response
GO:0042157 TAS:ReactomePlipoprotein metabolic process
GO:0042953 IEA:EnsemblPlipoprotein transport
GO:0060621 IMP:BHF-UCLPnegative regulation of cholesterol import
GO:0045717 IDA:BHF-UCLPnegative regulation of fatty acid biosynthetic process
GO:0010987 IMP:BHF-UCLPnegative regulation of high-density lipoprotein particle clearance
GO:0050995 IDA:BHF-UCLPnegative regulation of lipid catabolic process
GO:0045833 IDA:BHF-UCLPnegative regulation of lipid metabolic process
GO:0051005 IDA:BHF-UCLPnegative regulation of lipoprotein lipase activity
GO:0010989 IMP:BHF-UCLPnegative regulation of low-density lipoprotein particle clearance
GO:0048261 IDA:BHF-UCLPnegative regulation of receptor-mediated endocytosis
GO:0010897 IDA:BHF-UCLPnegative regulation of triglyceride catabolic process
GO:0010916 IDA:BHF-UCLPnegative regulation of very-low-density lipoprotein particle clearance
GO:0010903 IDA:BHF-UCLPnegative regulation of very-low-density lipoprotein particle remodeling
GO:0033700 IDA:BHF-UCLPphospholipid efflux
GO:0007603 TAS:ReactomePphototransduction, visible light
GO:0032489 IDA:BHF-UCLPregulation of Cdc42 protein signal transduction
GO:0042493 IEA:EnsemblPresponse to drug
GO:0007584 IEA:EnsemblPresponse to nutrient
GO:0043434 IEA:EnsemblPresponse to peptide hormone
GO:0001523 TAS:ReactomePretinoid metabolic process
GO:0043691 IC:BHF-UCLPreverse cholesterol transport
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0019433 IDA:BHF-UCLPtriglyceride catabolic process
GO:0070328 IMP:BHF-UCLPtriglyceride homeostasis
GO:0006641 IMP:HGNCPtriglyceride metabolic process
GO:0006642 IEA:EnsemblPtriglyceride mobilization
GO:0034379 TAS:BHF-UCLPvery-low-density lipoprotein particle assembly
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6841Chylomicron-mediated lipid transport
REACT_116125Disease
REACT_160102Diseases associated with visual transduction
REACT_13621HDL-mediated lipid transport
REACT_602Lipid digestion, mobilization, and transport
REACT_6823Lipoprotein metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_24968Retinoid metabolism and transport
REACT_111102Signal Transduction
REACT_160125Visual phototransduction
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