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MGP000230

Record overview

MGPD IDMGP000230
Gene ID467
SpeciesHomo sapiens (Human)
Gene Nameactivating transcription factor 3
Gene Symbol ATF3
Alternate namescyclic AMP-dependent transcription factor ATF-3; cAMP-dependent transcription factor ATF-3;
Chromosome1
Map Location1q32.3
SummaryThis gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011]
OrthologsView orthologs and multiple alignments for ATF3

Proteins

cyclic AMP-dependent transcription factor ATF-3 isoform 1
Refseq ID:NP_001665
Protein GI:4502263
UniProt ID:P18847
mRNA ID:NM_001674
Length:181
RefSeq Status:
MMLQHPGQVSASEVSASAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAA
AKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRAQNGRTPEDERNLFIQQIKEGTLQS
 
cyclic AMP-dependent transcription factor ATF-3 isoform 1
Refseq ID:NP_001025458
Protein GI:71902536
UniProt ID:P18847
mRNA ID:NM_001030287
Length:181
RefSeq Status:
Protein sequence is identical to GI:4502263 (mRNA isoform)
 
cyclic AMP-dependent transcription factor ATF-3 isoform 2
Refseq ID:NP_001035709
Protein GI:95102483
UniProt ID:P18847
mRNA ID:NM_001040619
Length:135
RefSeq Status:
MMLQHPGQVSASEVSASAIVPCLSPPGSLVFEDFANLTPFVKEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAA
AKCRNKKKEKTECLQKLPRPFWVQKTCIWAVDSCK
 
cyclic AMP-dependent transcription factor ATF-3 isoform 3
Refseq ID:NP_001193413
Protein GI:346223458
UniProt ID:P18847
mRNA ID:NM_001206484
Length:124
RefSeq Status:
MSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKTECLQKESEKLESVNAELKAQIEELKNEKQHLIYMLNLHRPTCIVRA
QNGRTPEDERNLFIQQIKEGTLQS
 
cyclic AMP-dependent transcription factor ATF-3 isoform 3
Refseq ID:NP_001193417
Protein GI:346223461
UniProt ID:P18847
mRNA ID:NM_001206488
Length:124
RefSeq Status:
Protein sequence is identical to GI:346223458 (mRNA isoform)
 
cyclic AMP-dependent transcription factor ATF-3 isoform 5
Refseq ID:NP_001193415
Protein GI:330417916
UniProt ID:P18847
mRNA ID:NM_001206486
Length:106
RefSeq Status:
MMLQHPGQVSASEEELRFAIQNKHLCHRMSSALESVTVSDRPLGVSITKAEVAPEEDERKKRRRERNKIAAAKCRNKKKEKTECLQKLPRPFWVQKTCIW
AVDSCK
 
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