MGP Database

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MGP000230

Ontology/Pathway Information

Entrez Gene ID467
Gene Nameactivating transcription factor 3
Gene Symbol ATF3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005730 IDA:HPACnucleolus
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:HPACnucleus
GO:0042802 IPI:IntActFidentical protein binding
GO:0000978 IEA:EnsemblFRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA:EnsemblFRNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0000977 IDA:NTNU_SBFRNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 IC:NTNU_SBFRNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 TAS:ProtIncFsequence-specific DNA binding transcription factor activity
GO:0003714 TAS:ProtIncFtranscription corepressor activity
GO:0006987 TAS:ReactomePactivation of signaling protein activity involved in unfolded protein response
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0030968 TAS:ReactomePendoplasmic reticulum unfolded protein response
GO:0006094 IEA:EnsemblPgluconeogenesis
GO:0008284 IEA:EnsemblPpositive regulation of cell proliferation
GO:0045944 IDA:NTNU_SBPpositive regulation of transcription from RNA polymerase II promoter
GO:0035914 IEA:EnsemblPskeletal muscle cell differentiation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18355ATF4 activates genes
REACT_17015Metabolism of proteins
REACT_18277PERK regulates gene expression
REACT_18356Unfolded Protein Response (UPR)
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