MGP Database

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MGP000321

Record overview

MGPD IDMGP000321
Gene ID650
SpeciesHomo sapiens (Human)
Gene Namebone morphogenetic protein 2
Gene Symbol BMP2
SynonymsBDA2; BMP2A;
Alternate namesbone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A;
Chromosome20
Map Location20p12
SummaryThe protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for BMP2

Proteins

bone morphogenetic protein 2 preproprotein
Refseq ID:NP_001191
Protein GI:4557369
UniProt ID:P12643
mRNA ID:NM_001200
Length:396
RefSeq Status:
MVAGTRCLLALLLPQVLLGGAAGLVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLYRRHSGQPGSPAPDHRLE
RAASRANTVRSFHHEESLEELPETSGKTTRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKFPVTRLLDTRLVNQN
ASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSLHQDEHSWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHP
LYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
 
sig_peptide: 1..23
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2238
peptide sequence: 
MVAGTRCLLALLLPQVLLGGAAG

mat_peptide: 283..396
product: bone morphogenetic protein 2
calculated_mol_wt: 12905
peptide sequence: 
QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVL
KNYQDMVVEGCGCR
 
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