MGP Database

MGP000323

Ontology/Pathway Information

Entrez Gene ID	655
Gene Name	bone morphogenetic protein 7
Gene Symbol	BMP7
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0031012	IEA:Ensembl	C	extracellular matrix
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	IDA:UniProtKB	C	extracellular space
GO:0031988	IEA:Ensembl	C	membrane-bounded vesicle
GO:0008201	IEA:Ensembl	F	heparin binding
GO:0007411	IEA:Ensembl	P	axon guidance
GO:0030509	IDA:BHF-UCL	P	BMP signaling pathway
GO:0060445	IEA:Ensembl	P	branching involved in salivary gland morphogenesis
GO:0048754	IEA:Ensembl	P	branching morphogenesis of an epithelial tube
GO:0051216	IEA:UniProtKB-KW	P	cartilage development
GO:0071456	ISS:BHF-UCL	P	cellular response to hypoxia
GO:0016358	TAS:BHF-UCL	P	dendrite development
GO:0048596	IEA:Ensembl	P	embryonic camera-type eye morphogenesis
GO:0030326	IEA:Ensembl	P	embryonic limb morphogenesis
GO:0009880	IEA:Ensembl	P	embryonic pattern specification
GO:0060272	IEA:Ensembl	P	embryonic skeletal joint morphogenesis
GO:0030855	IEA:Ensembl	P	epithelial cell differentiation
GO:0001837	TAS:HGNC	P	epithelial to mesenchymal transition
GO:0030198	TAS:Reactome	P	extracellular matrix organization
GO:0040007	IEA:InterPro	P	growth
GO:0048762	IDA:UniProtKB	P	mesenchymal cell differentiation
GO:0060485	ISS:UniProtKB	P	mesenchyme development
GO:0001707	IEA:Ensembl	P	mesoderm formation
GO:0001823	IEP:UniProtKB	P	mesonephros development
GO:0072136	IEA:Ensembl	P	metanephric mesenchymal cell proliferation involved in metanephros development
GO:0072133	IEA:Ensembl	P	metanephric mesenchyme morphogenesis
GO:0001656	IEP:UniProtKB	P	metanephros development
GO:0070487	IDA:UniProtKB	P	monocyte aggregation
GO:0045786	IDA:HGNC	P	negative regulation of cell cycle
GO:0060548	IDA:UniProtKB	P	negative regulation of cell death
GO:0072125	IDA:UniProtKB	P	negative regulation of glomerular mesangial cell proliferation
GO:0043407	IDA:UniProtKB	P	negative regulation of MAP kinase activity
GO:0072040	IEA:Ensembl	P	negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis
GO:0045839	IDA:UniProtKB	P	negative regulation of mitosis
GO:0045665	IDA:MGI	P	negative regulation of neuron differentiation
GO:0042347	ISS:BHF-UCL	P	negative regulation of NF-kappaB import into nucleus
GO:0032088	ISS:BHF-UCL	P	negative regulation of NF-kappaB transcription factor activity
GO:0045746	IEA:Ensembl	P	negative regulation of Notch signaling pathway
GO:0042326	IDA:UniProtKB	P	negative regulation of phosphorylation
GO:0060686	IEA:Ensembl	P	negative regulation of prostatic bud formation
GO:0010664	ISS:BHF-UCL	P	negative regulation of striated muscle cell apoptotic process
GO:0045892	IDA:UniProtKB	P	negative regulation of transcription, DNA-templated
GO:0072134	IEA:Ensembl	P	nephrogenic mesenchyme morphogenesis
GO:0048812	IDA:MGI	P	neuron projection morphogenesis
GO:0042475	IEA:Ensembl	P	odontogenesis of dentin-containing tooth
GO:0001503	IEA:UniProtKB-KW	P	ossification
GO:0043065	IEA:Ensembl	P	positive regulation of apoptotic process
GO:0030501	IDA:BHF-UCL	P	positive regulation of bone mineralization
GO:1900006	IDA:BHF-UCL	P	positive regulation of dendrite development
GO:0034116	IDA:UniProtKB	P	positive regulation of heterotypic cell-cell adhesion
GO:1900106	IDA:UniProtKB	P	positive regulation of hyaluranon cable assembly
GO:0045669	IDA:BHF-UCL	P	positive regulation of osteoblast differentiation
GO:0010862	IDA:UniProtKB	P	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010800	IDA:BHF-UCL	P	positive regulation of peptidyl-threonine phosphorylation
GO:0045893	IDA:UniProtKB	P	positive regulation of transcription, DNA-templated
GO:0045944	IEA:Ensembl	P	positive regulation of transcription from RNA polymerase II promoter
GO:0034504	IDA:UniProtKB	P	protein localization to nucleus
GO:0060687	IEA:Ensembl	P	regulation of branching involved in prostate gland morphogenesis
GO:0060393	IDA:BHF-UCL	P	regulation of pathway-restricted SMAD protein phosphorylation
GO:2000121	ISS:BHF-UCL	P	regulation of removal of superoxide radicals
GO:0032355	IEA:Ensembl	P	response to estradiol
GO:0043434	IEA:Ensembl	P	response to peptide hormone
GO:0033280	IEA:Ensembl	P	response to vitamin D
GO:0001501	TAS:ProtInc	P	skeletal system development
GO:0060395	IDA:UniProtKB	P	SMAD protein signal transduction
GO:0043401	IMP:UniProtKB	P	steroid hormone mediated signaling pathway
GO:0001657	ISS:UniProtKB	P	ureteric bud development

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_150366	Elastic fibre formation
REACT_118779	Extracellular matrix organization
REACT_150331	Molecules associated with elastic fibres