MGP Database

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MGP000416

Ontology/Pathway Information

Entrez Gene ID837
Gene Namecaspase 4, apoptosis-related cysteine peptidase
Gene Symbol CASP4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0097169 IBA:GO_CentralCAIM2 inflammasome complex
GO:0005737 IBA:GO_CentralCcytoplasm
GO:0005789 IEA:UniProtKB-SubCellCendoplasmic reticulum membrane
GO:0072557 IBA:GO_CentralCIPAF inflammasome complex
GO:0005739 IEA:UniProtKB-SubCellCmitochondrion
GO:0072559 IBA:GO_CentralCNLRP3 inflammasome complex
GO:0004197 IBA:GO_CentralFcysteine-type endopeptidase activity
GO:0006915 TAS:ProtIncPapoptotic process
GO:0097194 IBA:GO_CentralPexecution phase of apoptosis
GO:0006508 TAS:ProtIncPproteolysis
GO:0042981 IEA:InterProPregulation of apoptotic process
GO:0050727 IBA:GO_CentralPregulation of inflammatory response
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_75776NOD1/2 Signaling Pathway
REACT_75913Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
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