MGP Database

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MGP000438

Ontology/Pathway Information

Entrez Gene ID890
Gene Namecyclin A2
Gene Symbol CCNA2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:MGICcytoplasm
GO:0001939 IEA:EnsemblCfemale pronucleus
GO:0001940 IEA:EnsemblCmale pronucleus
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:MGICnucleus
GO:0000086 TAS:ReactomePG2/M transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0007095 TAS:ProtIncPmitotic G2 DNA damage checkpoint
GO:0007067 IEA:UniProtKB-KWPmitotic nuclear division
GO:0031100 IEA:EnsemblPorgan regeneration
GO:0048146 IEA:EnsemblPpositive regulation of fibroblast proliferation
GO:0045893 IEA:EnsemblPpositive regulation of transcription, DNA-templated
GO:0007265 IEP:BHF-UCLPRas protein signal transduction
GO:0000079 IEA:InterProPregulation of cyclin-dependent protein serine/threonine kinase activity
GO:0010389 IEA:InterProPregulation of G2/M transition of mitotic cell cycle
GO:0032355 IEA:EnsemblPresponse to estradiol
GO:0033762 IEA:EnsemblPresponse to glucagon
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6954Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
REACT_6781APC/C:Cdc20 mediated degradation of mitotic proteins
REACT_267701APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
REACT_6828APC/C-mediated degradation of cell cycle proteins
REACT_6850Cdc20:Phospho-APC/C mediated degradation of Cyclin A
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_120956Cellular responses to stress
REACT_169274Cellular Senescence
REACT_1857Cyclin A/B1 associated events during G2/M transition
REACT_9029Cyclin A:Cdk2-associated events at S phase entry
REACT_1574Cyclin E associated events during G1/S transition
REACT_169185DNA Damage/Telomere Stress Induced Senescence
REACT_383DNA Replication
REACT_111214G0 and Early G1
REACT_1783G1/S Transition
REACT_2203G2/M Transition
REACT_1915G2 Phase
REACT_21267Mitotic G1-G1/S phases
REACT_21391Mitotic G2-G2/M phases
REACT_1156Orc1 removal from chromatin
REACT_6362Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
REACT_6837Regulation of APC/C activators between G1/S and early anaphase
REACT_829Regulation of DNA replication
REACT_21279Regulation of mitotic cell cycle
REACT_207Removal of licensing factors from origins
REACT_9003SCF(Skp2)-mediated degradation of p27/p21
REACT_169168Senescence-Associated Secretory Phenotype (SASP)
REACT_899S Phase
REACT_2148Switching of origins to a post-replicative state
REACT_2014Synthesis of DNA
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