MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000454

Ontology/Pathway Information

Entrez Gene ID926
Gene NameCD8b molecule
Gene Symbol CD8B
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031901 TAS:ReactomeCearly endosome membrane
GO:0009897 IEA:EnsemblCexternal side of plasma membrane
GO:0005576 IEA:UniProtKB-SubCellCextracellular region
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042101 NAS:UniProtKBCT cell receptor complex
GO:0015026 NAS:UniProtKBFcoreceptor activity
GO:0042288 NAS:UniProtKBFMHC class I protein binding
GO:0006955 NAS:UniProtKBPimmune response
GO:0050690 TAS:ReactomePregulation of defense response to virus by virus
GO:0050776 TAS:ReactomePregulation of immune response
GO:0042110 NAS:UniProtKBPT cell activation
GO:0007169 NAS:UniProtKBPtransmembrane receptor protein tyrosine kinase signaling pathway
GO:0016032 TAS:ReactomePviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_116125Disease
REACT_6185HIV Infection
REACT_6288Host Interactions of HIV factors
REACT_6900Immune System
REACT_11152Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACT_11200Nef Mediated CD8 Down-regulation
REACT_11149Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
REACT_6835The role of Nef in HIV-1 replication and disease pathogenesis
  logo